Search results for " techniques"
Article
Advances in Engineering of Protein-Based APIs
“Humanization techniques using complementary determining regions grafting or phage display have enabled the advancement of numerous antibody therapeutics (such as trastuzumab, pembrolizumab, and romos…
Article
Modeling the Degradation of mAb Therapeutics
Modeling the Degradation of mAb Therapeutics
Kinetic models can be used to study aggregation and fragmentation to help ensure stability.
By Anurag S. Rathore, Rohit Bansal
…
Article
Biopharmaceutical Process Development: 2018 Lessons and 2019 Predictions
…Chromatography Scale-Up: Don't Get Tied Down by Bed Height
• Combine Chromatography Techniques: Get the Right Purity/Yield of Protein
• Impurity Testing of Biologic Drug Products
• …
Article
Scalable Viral Vector Manufacturing
For example, single-use bioreactors, filtration, and chromatography techniques are suitable for virus production.
Due to the diversity of viruses, platform solutions are challenging to implement e…
Poster
Scalable Continuous Chromatography Process for Enhanced Efficiency in Biomanufacturing
For continuous chromatography, interest in techniques such as periodic counter current chromatography (PCC) is increasing.
In this poster presented at the Recovery XVIII conference, based on dat…
Article
Videos! SPR Applications in Protein Characterization
In these exclusive videos from the Biacore Analytical, Comparability and QC Symposium, Vienna, November 2017, industry thought-leaders share insights, tips, and techniques that illuminate how SPR with…
Article
Your Protein Purification Questions Discussed
Questions about chromatography techniques, troubleshooting tips and tricks, and the use of ÄKTA systems were submitted in writing by protein purifiers globally.
We have included the questio…
Article
Preclinical Evaluation of Product Related Impurities and Variants
Preclinical Evaluation of Product Related Impurities and Variants
The approaches for sample preparation of preclinical evaluation of safety and efficacy are addressed taking into consideration the s…
Article
Transformative Medicines Challenge FDA and Manufacturers
Transformative Medicines Challenge FDA and Manufacturers
New gene therapies and combination products require innovative regulatory approaches.
By Jill Wechsler …
Article
Reliability Rooms and the Move to Proactive Supply Chain Management
The supply-chain function is utilizing advanced analytical techniques to determine the optimum algorithm for each product and market. For example, for planning, teams typically look at the demand/supp…