Search results for " techniques" in Articles / App Notes

Article What's in Your SOP?
What’s in Your SOP? SOPs need to reflect a company’s specific manufacturing or other operations, says Susan Schniepp, distinguished fellow at Regulatory Compliance Associates. …

Article Reducing Cross-Contamination Risks in Process Chromatography
Going 3D Advanced manufacturing techniques like 3-D printing (i.e., additive manufacturing) can bring significant benefits to manufacturing processes. For example, a 3-D printed part can combi…

Article Handbook: Design of Experiments in Protein Production and Purification
Design of experiments (DoE) is a technique for planning experiments and analyzing the information obtained. The technique allows us to use a minimum number of experiments, in which we systematically v…

Article Development of Purification for Challenging Fc-Fusion Proteins
Materials and Methods Purification techniques Feed stock: Fc-fusion proteins with an isoelectric point (pI) ranging from four to seven were expressed in recombinant Chinese h…

Article Modeling and Miniaturization: Key Topics at Successful HTPD Conference
The second downstream session,“Case Studies Downstream Part II: Other Techniques,” chaired by Ashley Hesslein from Bayer HealthCare, not only covered additional techniques such as cross flow filtratio…

Article Reconciling Sensor Communication Gaps
Whatever techniques are ultimately adopted, their ultimate goal must be to eliminate manual sampling and lengthy analyses, or at least, to streamline these operations so they become relevant within th…

Article Evaluating E&L Studies for Single-Use Systems
These solutions were recirculated in each skid for a few hours up to seven days at normal process temperature, then sampled and analyzed by performing the different techniques. The reference solutions…

Article Affinity chromatography Handbook - Vol. 3: Specific Groups of Biomolecules
Affinity chromatography (AC) separates proteins on the basis of a reversible interaction between a protein (or group of proteins) and a specific ligand coupled to a chromatography matrix. The techni…

Article A Platform Approach for the Identity Testing of Multi-Component Cell-Culture Media
Several spectroscopic non-destructive techniques, including Fourier Transform Infrared (FT–IR), near-infrared (NIR), and Raman spectroscopy have been used for the identification and characterization o…

Article Antibody Production in Microbial Hosts
Though substantial progress has been made in cellular engineering and in the secretion pathway of microbial cells, further progress in metabolomic and proteomic techniques is required to improve the u…

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