Search results for " protein"
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Improvements in Protein A Chromatography
Bolton recently published a paper “Role of more than 40 years of improvement in Protein A chromatography in the growth of the therapeutic antibody industry,” and also presented at the spring ACS meeti…
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Top challenges in recombinant protein purification process development
Cytiva™ Protein Select™ resin is designed overcome some of these challenges.
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Jeanne Linke Northrop: Hello, I'm Jeanne Linke Northrop with BioPharm International…
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Platform Technologies Improve Protein Expression
In addition to exploring novel production methods such as continuous processes and disposable production technology, manufacturers also heavily invest in platform technologies for protein expression t…
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Development and Future of Protein A Chromatography Technology: Q&A with Jonathan Royce, Business Leader Chromatography Resins, Cytiva
In the last decade, significant development has also been made in the area of Protein A, both in term of binding capacity and stability, as discussed in a previous Q&A session. What do you feel are th…
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Comparing Protein A Resins for Monoclonal Antibody Purification
A team from Chugai Pharmaceutical (Japan) investigated the mAb purification performance of a new alkali-tolerant, prototype Protein A resin (Resin 3, MabSelect SuRe LX prototype, Cytiva), which has th…
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N-Glycan Analysis of Biotherapeutic Proteins
More than half of all biotherapeutics are glycosylated (2), including monoclonal antibodies (mAbs), Fc-fusion proteins, clotting factors, and cytokines such as erythropoietin. Of these, mAbs represent…
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Webinar about a new affinity chromatography technology for recombinant proteins
During a simple affinity step, the protein self-cleaves from the tag and elutes with no residual tag amino acids. The protocol does not require the use of a protease, and the same buffer can be used f…
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FAQs about Cytiva™ Protein Select™ technology
Purifying a protein tagged with this technology is simple. One chromatography step does the affinity purification, a traceless tag cleavage, and the tag removal. The pure protein obtained is in its na…
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Video: Standardize recombinant protein purification process development
During an affinity step performed with Cytiva Protein Select resin, the protein self-cleaves from the tag and elutes with no residual tag amino acids.
This technology standardizes purification duri…
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Understanding Protein Production from Start to Finish
Most scientists working with exploring proteins and developing specific target biomolecules use several steps including cell culture, sample preparation, purification, and analysis. This requires unde…