Search results for " protein" in Articles / App Notes
Article
Eliminating Residual Impurities Starts with a Strategic Plan
Others are more complex to define, such as those that originate from the cellular system including residual DNA or host-cell proteins (HCPs),” Wake observes. “In the latter case, for instance, conside…
Article
Gene Therapies Push Viral Vector Production
Infectivity, he explains, is usually dictated by the envelope proteins present in a virus and the cellular surface components to which those proteins bind. “Depending on the application, the ideal vec…
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Webinar On Demand: Expanding SPR Uses in Antibody Effector Function Determination
CQAs typically include data on how the candidate interacts with target proteins, as well as process-related CQAs such as protein size, homogeneity, presence of host cell proteins (HCP) etc.
In th…
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An Analytical Approach to Biosimilar Drug Development
As a result, demand has increased for chromatography and mass spectrometry technology providers to design instrumentation, software informatics, and workflows to support protein analysis studies. In a…
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Why, Why, Why…ELISA? A Look at the Benchmark HCP Assay
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Biologics developers and manufacturers demand an accurate and reliable assay for host cell protein (HCP) quantitation. Let’s take a close look at why analytica…
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News: Cytiva Adds ELISA Kit to End-to-End HCP Monitoring Capabilities
Cytiva is pleased to announce the new Amersham HCPQuant CHO kit, a generic for detecting host cell protein impurities in drug samples produced in CHO cell lines.
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Four Purification Steps with Buffer Dilutions in One Go? No Problem!
Learn how Shin Isogai at Biozentrum, Basel, harnesses automation to purify more proteins per week using ÄKTA pure, giving himself more time for other tasks.
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Increase Throughput with Automation in Multistep Purification
When there is simply not enough time to purify proteins needed or when everyone has too much to do, automation can be the answer for multistep protein purification. See how a biotech startup uses auto…
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Ensuring Viral Safety of Viral Vaccines and Vectors
Gamma irradiation—ionizing radiation from a radioactive Cobalt 60 source—breaks bonds in nucleic acids and proteins. This method is widely used in the biopharmaceutical industry to treat bovine serum …
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Selection Guide: Columns and Resins for Antibody Purification and Immunoprecipitation
Polyclonal antibodies, monoclonal antibodies (mAbs), and antibody fragments are usually purified by affinity chromatography. Resins containing an immobilized ligand (e.g., protein A, protein G, or p…