Search results for " protein" in Articles / App Notes
Article
Optimization of a two-step purification method for bispecific antibodies
Bispecific antibodies (bsAbs) have gained increasing interest over recent years because they can bind two antigens, offering unique modes of action compared to monoclonal antibodies. New and i…
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Announcing ÄKTA ready™ extended single-use system
ÄKTA ready™ extended system is a single-use liquid chromatography system designed for process scale-up and GMP manufacturing.
The system uses disposable flow paths and prepacked …
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What is process development?
Biopharma process development comprises the activities that help you create a series of steps to produce a biomolecule – a monoclonal antibody (mAb), recombinant protein, viral vector, or other produc…
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Top Process Development Trends for 2022 and a Look into 2023
The article, “Next-generation Protein L Chromatography,” for example, begins by establishing that the diversity of antibody variants in today’s pipeline presents unique challenges for purification pro…
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Report from the 12th Plasma Product Biotechnology Forum
The model output was a prediction of yield and purification rate, and the input included feed flowrate, conductivity, column loading, and total protein concentration. One of the conclusions from the s…
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Sign-up to join Chromatography Virtual Summit 2022
Latest advancements in chromatography process development.
Go smarter. Go faster.
Virtual event 15–17 November 2022
Join the Cytiva chromatography summit online to l…
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Need solutions for large-scale production of mRNA-based molecules?
mRNA therapeutics offer precise and individualized therapy and avoid manufacturing issues associated with recombinant proteins. Compared with current therapeutics, mRNA production is more cost-effecti…
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Rethinking ion exchange chromatography modeling
It is based on a colloidal description of proteins, and, in comparison to the standard steric mass adsorption (SMA) model, it achieves increased accuracy at high column loading.
Read m…
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Trends in Outsourcing of Bioprocess Development
Growing numbers of conventional recombinant proteins and monoclonal antibodies, as well as next-generation molecules such as multispecifics, antibody-drug conjugates, and cell and gene therapies, are …
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Optimization of a Two-Step Purification Method for Bispecific Antibodies
Alligator Bioscience AB develops antibody-based pharmaceuticals for cancer treatment, specializing in mono- and bispecific antibodies for tumor-directed immunotherapies. Alligator and Cytiva devel…