Search results for " protein" in Articles / App Notes
Article
Asked and Answered: Your Questions on Ion-Exchange Chromatography
Check out what questions your fellow protein purifiers have related to ion-exchange chromatography.
The questions are organized in by chief concern, and include buffers, experimental design, L…
Article
Hybrid Bioprocessing: A Q&A with Andrew Sinclair
In the therapeutic protein space, there has not been a truly SU facility at commercial scale.
What could be the main reasons and/or the main drivers that hybrid bioprocessing are being used? Is th…
Article
Sources of Bioburden You Might Have Missed
A problem with traditional mAb manufacturing is that there are so many potential entry points for microbial contamination. There are, however, ways to shut the door on contamination.
The risk …
Article
Cost Considerations Drive Lean Technology in Biopharmaceutical Manufacturing
Essential Pharmaceuticals provides an animal-component free media that boosts titer and enhances protein quality. It can be difficult to change or improve processes with the strict regulations around …
Article
Single-use Bioreactors Have Reached the Big Time
“[Cytiva] is taking its experience in single-use bioreactor technologies for monoclonal antibody, recombinant protein, and vaccine processes and applying it in our Xuri line of cell therapy equipment …
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Increase Efficiency in Experimentation with Design of Experiments
Setting up an efficient study can help you save time and allow you to get the most out of screening and optimization experiments during method development. Also, good planning and relevant experimen…
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Efficient Purification of Pneumococcal Polysaccharides in a Chromatography Workflow
This application note demonstrates the purification of pneumococcal capsular polysaccharides using chromatography. The described process constitutes a viable alternative to the traditional process f…
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Establishing Acceptance Criteria for Analytical Methods
Recommended Acceptance Criteria for Specificity
There are two ways to show specificity:
• Identification, demonstrate it is measuring the specific analyte and not some other protein or substan…
Article
Technology solutions simplifying chromatography unit operations
This application note describes how modern tools and technology solutions can help facilitate chromatography operations for an effective and productive protein purification process.
Download the a…
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Vocabulary of the chromatographer
Similar to other technical areas, chromatographers generate their own vocabulary, all with a good scientific purpose and for a common understanding. However, the same terminology can be used in othe…