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Article Cost Considerations Drive Lean Technology in Biopharmaceutical Manufacturing
For the earliest biologics, patents have expired or are near expiration, opening the door for follow-on generic product competitions. FDA approved the first Humira (adalimumab) biosimilar, Amjevita (A…

Article Improving Process-Scale Chromatography
Advances in technology are increasing the productivity and efficiency of commercial-scale chromatography bioprocesses. By Cynthia Challener, PhD Chromatography is a crucial step in the purif…

Article Perfusion in the 21st Century
Quality, flexibility, and cost savings are driving use of perfusion technology in biosimilars manufacturing. By Bruce Lehr, Delia Lyons Cell-culture technology for biopharmaceutical manufact…

Article Biosimilars: Making the Switch Comes with Challenges
More efforts are needed to raise awareness of biosimilars among physicians and patients in Europe and address scepticisms about the quality and safety of biosimilars. By Sean Milmo The use o…

Article Designing a Biomanufacturing Facility Incorporating Single-Use Technologies
Asking the right questions is crucial to establishing a facility design. By Peter Genest, John Joseph The benefits of adopting single-use technologies in the production of biopharmaceuticals…

Article Continuous Processing for the Production of Biopharmaceuticals
The authors review the technologies that may help bioprocessing become a truly continuous operation and present case studies that could contribute to the integration of upstream and downstream platf…

Article Finding Opportunities in Brazil
Feb 06, 2015 By Hellen Berger BioPharm International Volume 28, Issue 2 Brazil’s turbulent presidential election in October 2014 shed some light on the country’s political landscape …

Article FDA Approves First Biosimilar
Mar 06, 2015 By Randi Hernandez BioPharm International FDA approved Sandoz’s Zarxio (filgrastim-sndz) on March 6, 2015. The approval is a groundbreaking decision, as Sandoz is the firs…

Article New Era for Generic Drugs
Manufacturers face regulatory overhaul, while brand-generic debates escalate over biosimilars and labeling changes. Nov 1, 2014 By: Jill Wechsler BioPharm International Volume 11, Issue …

Article Pharma Investments Reflect Key Industry Trends
Shrinking facility size, growth of biologics, and emerging market demand influence pharma investments. Aug 2, 2014 By: Cynthia Challener, PhD Pharmaceutical Technology Volume 37, Iss…

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