Search results for " comparability" in Posters
Poster
Evaluation of Protein A resin lifetime during extensive use (overloading) in continuous chromatography mode
In recent years, continuous chromatography has emerged as an alternative to batch operations to improve productivity or increase resin capacity utilization of chromatography purification processes. …
Poster
Heating-cooling and liquid-liquid mixing characterization at a range of volumes
In a biopharmaceutical plant, more that 50% of the operation is mixing or hydration. Single-use mixers have been used in the past two decades in biopharmaceutical plants to replace the use of stainl…
Poster
Validation of Cytodex™ Gamma microcarrier-based virus production in single-use bioreactor systems
A majority of cell lines commonly used for viral vaccine production are anchorage-dependent and require expansion on solid surfaces. Here, we describe different approaches for the cultivation of Ver…
Poster
Columns up to 1600 mm in diameter packed with protein A chromatography medium using axial mechanical compression
Axial compression allows for optimally packed beds also in the large-scale chromatography column range. Different methods have been developed to pack a broad range of chromatography media (resins) i…
Poster
Integration of continuous upstream and downstream operations in mAb production
Process intensification is gaining interest as a strategy to reduce production costs, while improving product quality and throughput in the manufacturing of biopharmaceuticals. For a competitive pro…
Poster
Process economy and production capacity using single-use versus stainless steel fermentation equipment
This white paper compares production capacity and process economy between stainless steel and single-use equipment in microbial processes. Economy simulations were based on an E. coli Dab process. P…