Search results for "Cytiva"
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Automated Buffer Preparation with Inline Conditioning Technology
Inline conditioning (IC) technology allows for buffers to be produced from single-component stock concentrates when needed, at the point-of-use (POU). IC automates buffer production, s…
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What Makes a High-Quality Chromatography Resin?
Learn the process of what makes a high-quality chromatography resin.
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Connected Inline Conditioning for Better Process Efficiency
In this study, we integrated an inline conditioning (IC) system that served as a buffer preparation skid with chromatography and filtration systems. This automated the buffer preparation p…
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Dynamic Binding Capacity in Fiber-Based Chromatography
Fiber-based matrices for affinity purification is suitable for rapid-cycling chromatography. Fiber chromatography matrices such as Fibro PrismA can bind a large amount of protein in a frac…
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Good Modeling Practice
How to ensure accurate model calibration for your mechanistic models.
Mechanistic models have become a very promising technique to describe chromatography processes. These models …
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Designing a 1.5 L Bench-Scale Model of a Perfusion Process
Establishing an appropriate model allows for higher throughput during simultaneous operation and monitoring of several cultures at different process conditions. In this article, we discus…
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Establishing a Robust Workflow to Identify GOCHO™ Clones
Cell line development is typically on the critical path of drug development. It’s a complex, labor intensive, and multistep process. Our new cell line development platform uses the GOCHO™…
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Optimization of a HIC step for recombinant protein purification
Follow this step-by-step high-throughput process development (HTPD) workflow to determine the optimal resin and initial conditions for hydrophobic interaction chromatography (HIC).
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From cells to purified capsids: How to develop a scalable rAAV process
Adeno-associated virus (AAV) is the most common vector for gene therapy, yet there’s much room to improve production, purification, and analytics. In this webinar we present the latest upd…
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Scaling a mAb production process to Xcellerex bioreactors
Moving a monoclonal antibody production process from a microscale bioreactor to the Xcellerex XDR single-use platform.
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