Search results for "Cytiva"
Article
Walk Away and Do More Screening Preps
Developing a process or looking for a clone of interest often requires screening large numbers of samples. Many analyses require purified protein, and substantial hands-on time might be allocated to…
Article
Development of column packing methods based on pressure flow measurements
Scale-up of a chromatography process might appear as simply increasing the column diameter to accommodate for the higher quantity of material to be processed, while maintaining the same bed height …
Article
Validation of the production of influenza virus in ReadyToProcess WAVE™ 25 bioreactor system
This application note describes the validation of the single-use ReadyToProcess WAVE 25 rocking bioreactor system in production of influenza virus from Vero cells in microcarrier-based cultures. A 2…
Article
A Platform Approach to Purification of Antibody Fragments
Antibody fragments constitute a promising class of biopharmaceutical products. As compared with full length antibodies, their fragments have unique properties that make them favorable for certain th…
Poster
Scale-up and process economy calculations of a dAb purification process using ready-to-use products
Purification of a domain antibody (dAb) in a chromatography capture step was successfully scaled from laboratory to pilot scale using ready-to-use equipment and ready-made buffers. The scaled-up pro…
Poster
Validation of Cytodex™ Gamma microcarrier-based virus production in single-use bioreactor systems
A majority of cell lines commonly used for viral vaccine production are anchorage-dependent and require expansion on solid surfaces. Here, we describe different approaches for the cultivation of Ver…
Poster
Guide to modern BioProcess™ chromatography resins
Proteins are different. Based on what protein you would like to purify and the conditions used, chromatography resins are selected to optimize purity and yield. Many bioprocess applications include …
Poster
Scale-up of CHO fed-batch cultures in HyClone™ ActiPro™ medium supplemented with Cell Boost™ 7a and 7b
Comparing cell growth and recombinant protein production of multiple Chinese hamster ovary (CHO) cell clones when cultured in HyClone ActiPro basal medium and Cell Boost 7a and 7b feeding supplement…
Poster
Improve operational efficiency in biomanufacturing with comprehensive automation solutions
In the biopharmaceutical industry, process data is used in multiple ways throughout process development and the different production phases. However, equipment used are often connected only by proce…
Article
Modeling Bioreactor Performance
…cale-down), according to Ken Clapp, senior manager for applications, integration, and technology at Cytiva. “Performance may be as much about the integration of the bioreactor in the overall biomanuf…