Search results for " scalable" in Articles / App Notes
Article
Recombinant Adeno-Associated Virus Type 5 Production Process
A scalable recombinant adeno-associated virus (rAAV) type 5 production process was developed using transfected HEK293 suspension cells.
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Cell culture process development for AAV vector production in suspension cells
Adaptation of HEK293 suspension cell line for transient transfection and scalable adeno-associated virus (AAV) production.
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Technology Innovations Improve Process Chromatography Performance
In this case, pressure is placed on the buffer train, so it is necessary to ensure that the buffer prep operation is efficient and scalable,” Deorkar states.
However, increasing the size of downst…
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Flexible Facilities for Viral Vector Manufacturing
Both options typically do not have scale limitations and thus would allow for a more scalable process.
The initial KUBio box for viral vector production was designed for a 200-L process scale, but…
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Mapping a Route for Cell and Gene Therapy Process Development
Reducing manufacturing costs, as well as development of scalable, automated manufacturing processes under closed systems that can reach the target quantities while maintaining the critical quality att…
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Single-Use for Downstream Chromatography: Benefit or Hindrance?
Single-use technology is gaining ground in downstream bioprocessing, but challenges stall further adoption.
By Feliza Mirasol
ARTMOIS/STOCK.ADOBE.COM
Biopharmaceutical manufactu…
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Science Focus Fuels Successful Process Development for Startups
Given the cost and time involved, being able to develop a practical and scalable process is essential to achieving success,” Sharei explains.
For Krystal Biotech, which is developing gene therapie…
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Case Study: Process for Production of Oncolytic Adenovirus
The case study describes a process from upstream cell culture to downstream purification, using scalable modern tools and technologies.
Read the case study on "Process for Production of Oncolytic…
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Biopharmaceutical Process Development: 2018 Lessons and 2019 Predictions
The biopharmaceutical industry continues to expand in new and exciting ways. What might be in store for 2019, and what important lessons should process developers take from 2018? Here, we look back …
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Scaling Up Novel Therapies
Chromatography and filter manufacturers have developed scalable and reproducible low-volume mimics of their industrial-scale equipment, which allow more accurate scale-up work than ever before, he say…