Search results for " method" in Articles / App Notes
Article
Principles and methods for automated multistep protein purification
Read principles Q&A blog post
Methods of Automated Multistep Protein Purification
Summarized questions related to methods of multistep processing.
Read methods Q&A blog post
Article
Process development using a nonaffinity method vs Cytiva™ Protein Select™ resin
The first method is using nonaffinity chromatography steps (AIEX + heat treatment + HIC), while the second method is using the novel affinity Cytiva™ Protein Select™ resin for the capture step, follow…
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Tips for Purification Method Editing: Learnings from the Webinar
Useful tips and features were demonstrated, for example how to develop methods that are easy to maintain, reuse, and share.
The live Q&A session after the webinar provided many interesting questi…
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Tips for Protein Purification Method Editing
Find out how to quickly generate tailored automation methods in your UNICORN™ software in this blog.
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Development of column packing methods based on pressure flow measurements
In practice, however, additional aspects such as method of column packing, hydrodynamic pressure drop, and efficiency of liquid flow distribution need to be considered. A typical problem to be addres…
Article
Filtration methods to overcome new challenges in viral safety
41 and ICH Q5A, and outlines the detailed mechanisms governing effective virus filtration, demonstrating how both specific methods and advanced filter design can overcome these challenges.
READ FUL…
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Perfusion Culture Using TFF or ATF as Cell Retention Method
…r tangential flow filtration (TFF) or alternating tangential flow filtration (ATF) as cell retention method.
Article
Connected Polishing and Concentration Under One Automation Method
One automation method was created for control of both systems. Single-use process components were used to add flexibility to the process.
Read full study here.
Article
Optimization of a two-step purification method for bispecific antibodies
Bispecific antibodies (bsAbs) have gained increasing interest over recent years because they can bind two antigens, offering unique modes of action compared to monoclonal antibodies. New and i…
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Optimization of a Two-Step Purification Method for Bispecific Antibodies
Alligator Bioscience AB develops antibody-based pharmaceuticals for cancer treatment, specializing in mono- and bispecific antibodies for tumor-directed immunotherapies. Alligator and Cytiva devel…