Search results for " efficiency"
Article
Resolving a bottleneck in screening and characterization of recombinant antibody fragments using Biacore 4000
Antibodies and their derivatives are increasingly important as biotherapeutics, precision diagnostics, and essential tools for biological research. Techniques to screen and characterize large number…
Article
A Risk-Based Genetic Characterization Strategy for Recombinant CHO Cell Lines Used for Clinical and Commercial Applications
The authors describe the ways in which manufacturers can mitigate the risks related to the integrity of recombinant transgenes expressed in CHO cells.
By Luhong He, Christopher Frye
Abstract
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Article
Changing the Culture of Cell Culture: Applying Best Practices and Authentication to Ensure Scientific Reproducibility
By Leonard P. Freedman, Mark C. Gibson, Richard M. Neve
Irreproducible preclinical research is a global, expensive, and well-recognized problem that contributes to delays and increased costs of …
Article
CMOs Concerned With Cost of Single-Use Equipment
Given that CMOs expect to increase their budgets by as much as 6% for new technologies to improve upstream and downstream efficiency—with single-use equipment presumably a part of this spending—budget…
Article
Optimizing Cation-Exchange Chromatography with High-Throughput Process Development for mAb Purification
Optimization of each phase in a chromatographic cycle has a positive impact on productivity.
By Anna Grönberg
An important area of focus for the biopharma industry is the elucidation and dev…
Article
SEC in the Modern Downstream Purification Process
Mar 01, 2015
By R. Christopher Manzari, J. Kevin O'Donnell
BioPharm International
Volume 3, Issue 28
Since the introduction of commercial chromatography resins approximately six de…
Article
DoE Provides Benefits, but Preparation Is Necessary
An added benefit of this efficiency, Yang notes, is the reduced quantity of material needed for formulation development, which can be important early in the development of a biopharmaceutical product …
Article
Continued Process Verification for Biopharma Manufacturing
A manufacturer may also wish to include measures of process efficiency, but beyond these two categories, adding additional measures to those taken during processing will not add significant value to t…
Article
Challenges and Trends in Biopharma Facility Design
Flexibility, cost efficiency, and speed are characterizing the new generation facilities. High-yield processes, single-use equipment, and modular concepts are tools contributing to the ability to meet…
Article
Q&A with Eric Langer, about the evolution of the role of CMO’s in Bioprocessing
Can you tell us why that is?
Eric: Based on our 11th Annual Report, this focus on productivity is changing the way companies outsource, For example, there’s been a real push for more efficiency …