Search results for " efficiency"
Article
Updating Viral Clearance for New Biologic Modalities
“As we look at new technologies for improving the efficiency of molecule separation, we always evaluate them based on their ability to remove a virus,” Verlenden says, noting that most downstream temp…
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Technology Innovations Improve Process Chromatography Performance
He adds that variability in raw materials can present serious issues that impact downstream efficiency and can lead to long investigations and potential delays in making drugs available for patients. …
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Process Chromatography: Continuous Optimization
Drug manufacturers are always seeking ways to improve the efficiency and productivity of chromatographic separations. Suppliers of chromatography resins are developing new resin chemistries and bindin…
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Digitalization: The Route to Biopharma 4.0
… reduce human intervention, automate process control, and perform fault detection to improve process efficiency.
However, there are many attributes such as charge variant, aggregates, host-…
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Enhancing Resins Addresses Purification Concerns
“Although the purification challenges for each modality are different, all downstream processes have the common goal of increasing yields with process efficiency in a cost-effective way while ensuring…
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Maximum Output Starts with Optimized Upstream Processing
Equipment suppliers, contract manufacturers, and biopharmaceutical companies are implementing new bioprocessing solutions and manufacturing strategies to increase efficiency and productivity, forging …
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Cell-Culture Advances Test Bioreactor Performance Models
To continue to drive efficiency and reduce cost of manufacturing while maintaining or improving quality, reducing bioreactor variation will be required, and predictive models can enable these variatio…
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2014 Manufacturing Trends and Outlook
Nearly half reported improved manufacturing efficiency as a result. However, almost 32% of the respondents have not implemented QbD. Reasons cited for not implementing QbD include a lack of guidance a…
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The Development and Application of a Monoclonal Antibody Purification Platform
The platform was developed to maximize the efficiency of the purification process and product purity while minimizing the development time for early-phase therapeutic antibodies. The success of this p…
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The Importance of Process Intensification and PAT for Achieving Real-Time Release
Lee and Mark Lies
Process intensification is of broad interest in the biopharmaceutical industry because of its promise and potential to increase efficiency and t…