Search results for " efficiency" in Articles / App Notes
Article
Maximum Output Starts with Optimized Upstream Processing
Equipment suppliers, contract manufacturers, and biopharmaceutical companies are implementing new bioprocessing solutions and manufacturing strategies to increase efficiency and productivity, forging …
Article
Cell-Culture Advances Test Bioreactor Performance Models
To continue to drive efficiency and reduce cost of manufacturing while maintaining or improving quality, reducing bioreactor variation will be required, and predictive models can enable these variatio…
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2014 Manufacturing Trends and Outlook
Nearly half reported improved manufacturing efficiency as a result. However, almost 32% of the respondents have not implemented QbD. Reasons cited for not implementing QbD include a lack of guidance a…
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The Development and Application of a Monoclonal Antibody Purification Platform
The platform was developed to maximize the efficiency of the purification process and product purity while minimizing the development time for early-phase therapeutic antibodies. The success of this p…
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The Importance of Process Intensification and PAT for Achieving Real-Time Release
Lee and Mark Lies
Process intensification is of broad interest in the biopharmaceutical industry because of its promise and potential to increase efficiency and t…
Article
Process Development: 2020 Reflections and 2021 Possibilities
Improving Process Development Efficiency
The COVID-19 pandemic has highlighted just how desperately effective approaches to improve efficiency in process development are needed for both developers…
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Best Practices for Selecting a Top-Quality Cell Line
…—with all product quality attributes consistent with the desired profile—with high manufacturing efficiency, according to Ian Collins, senior director of process development at Catalent. “A high-qual…
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A Look at the Affinity Chromatography Landscape
A Look at the Affinity Chromatography Landscape
New ligands are being developed to meet the separation and purification needs of next-gen biologics.
By Cynthia A. Challener
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Development of Purification for Challenging Fc-Fusion Proteins
Development of Purification for Challenging Fc-Fusion Proteins
This study outlines methods for an alternative protein-polishing process for challenging proteins.
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Impact of Media Components on CQAs of Monoclonal Antibodies
Hydrocortisone improves the cloning efficiency of the glial cells and fibroblasts (2). Along with hydrocortisone and prolactin, various combinations of estrogen, androgens, and progesterone are necess…