Search results for "vaccine"
Article
New Therapies Present Scaling Challenges
New Therapies Present Scaling Challenges
Manufacturing differences between traditional mAb therapies and newer biotherapeutics dictate whether processes should be scaled up, scaled out, or use an al…
Article
What’s New in Upstream Technologies
The system features a modular, scalable, fixed-bed bioreactor for enhanced upstream processing of viral products, including viral vaccines, viral vectors, and oncolytic viruses. The low-footprint inte…
Article
Case Study: Process for Production of Oncolytic Adenovirus
The promising results from clinical studies on the use of viral vectors to address important medical needs have spurred interest in developing scalable and cost-efficient manufacturing processes. Here…
Article
Achieve Scalable Viral Vector Production
In our tutorial series on viral vector production, Cytiva scientists share their insights on virus production and how to tackle viral vector manufacturing challenges. In this episode, a scalable produ…
Article
Biopharmaceutical Process Development: 2018 Lessons and 2019 Predictions
…aration of Charged mAb Variants
• Modern Manufacturing Key to More Effective Vaccines
• Evaluation of Performance of a Disposable mAb Affinity Chromatography Column Used Over Multiple Pro…
Article
A Look at the Affinity Chromatography Landscape
In a pandemic situation, he notes that production of 40 million doses of flu vaccine is possible in one day with 54 L of membrane.
Nanofibers for affinity chromatography
A number of different …
Article
Recent Advances in the Use of Exoglycosidases to Improve Structural Profiling of N-glycans from Biologic Drugs
… important roles in other clinically important areas, such as cellular or protein glycoengineering, vaccine development, and molecular diagnostics.
Acknowledgements
The authors thank Barbara …
Poster
A Scalable Adenovirus Production Process
The promising results from clinical studies on the use of viral vectors to address important medical needs have spurred interest in developing scalable and cost-efficient manufacturing processes. To…
Article
Process Economic Simulation for Scalable Production of Adenovirus
This application note discloses the process economic modelling of a modern start-to-finish adenovirus production process. The novel process was compared with a reference process in both stainless-st…
Article
Biopharma Says It Has an Evolution in New Technologies and Processes
Cytiva introduced prefabricated, modular KUBio manufacturing units for the production of viral vector-based therapeutics including viral-vector based vaccines, oncolytic viruses, and gene and cell the…