Search results for "Recovery"
Article
Nurturing Knowledge from Disparate Data Streams
“It may be argued, for example, that the relatively simple process of recovering and reviewing chart recordings from a well-maintained paper archive has advantages over the recovery of data from older…
Article
Supply Chain Challenges for Single-Use Systems
…g/forecasting, capacity planning, business continuity planning, change control management, disaster recovery planning, supply-chain mapping, and continuous improvement. At MilliporeSigma, a cross-fun…
Poster
Scalable Continuous Chromatography Process for Enhanced Efficiency in Biomanufacturing
In this poster presented at the Recovery XVIII conference, based on data from a collaboration between Merck and Cytiva, we use two case studies to demonstrate that PCC is a robust and scalable technol…
Article
Challenges in Cell Harvesting Prompt Enhancements
al, “Recovery and Purification Process Development for Monoclonal Antibody Production,” MAbs online, DOI: 10.4161/mabs.2.5.12645, Sept. 1, 2010.
Article
Evaluation of Performance of a Disposable mAb Affinity Chromatography Column Used Over Multiple Process Cycles
Analysis of mAb purity and recovery as well as column bed integrity testing show that the column can be used with maintained performance for at least 50 cycles, providing significant process economic …
Article
Multidimensional Scale-Up of a Monoclonal Antibody Capture Step, Using ÄKTA™ pilot 600
Equivalent mAb recovery and purity was achieved between the larger and the smaller scales, showing a robust and scalable process.
Click here to view the application note.
Article
Concentration and Buffer Exchange Using the Automated, Single-Use ÄKTA™ readyflux System
Protein recovery was ≥ 99%, after 5‑times concentration and 5‑fold diafiltration. The process was performed according to set specifications for a tangential flow filtration (TFF) process, with the…
Article
Process Chromatography: Continuous Optimization
The result, according to Westman, is high-purity recovery under generic conditions in just one separation step and enables a plug-and-play approach that leads to reduced process development times. In …
Article
The New World of Biopharmaceutical Manufacturing
They will also be integrated into recovery/purification and be operated in semi-continuous or continuous mode. The number of drugs that are produced by non-mammalian expression systems, such as yeast …
Poster
Impact of sporicidal agent on MabSelect SuRe™ protein A resin lifetime
The results show that treatment with 20 mM PAA for 30 min or 30 mM PAA for 15 min could be used without significantly affecting mAb recovery or purification performance of the resin, as compared with …