Search results for " variability"

Article Biopharma Advances Demand Specialized Expertise
… Process analytical technology (PAT) for continuous monitoring of bioprocesses is helping reduce the variability on biopharmaceutical manufacturing. Also, biopharmaceutical development and proces…

Article Ensuring the Quality of Biologicals
May 02, 2015 By Stephen Wicks, PhD Pharmaceutical Technology Volume 39, Issue 5 The European Pharmacopoeia (Ph. Eur.), which celebrated its 50th anniversary in 2014, provides common …

Article Re-use of Protein A Resin: Fouling and Economics
Mar 01, 2015 By Anurag S. Rathore, Mili Pathak, Guijun Ma, Daniel G. Bracewell BioPharm International Volume 3, Issue 28 In the past two decades, Protein A affinity chromatography ha…

Article Detecting Protein Aggregates and Evaluating their Immunogenicity
“Because of this variability in measurements using different techniques, it is usually necessary to use multiple, orthogonal techniques,” says Brown. According to Brown, there are no standard referenc…

Article Securing the Single-Use Supply Chain
“These results indicated that the materials were comparable within the variability of the analytical techniques used,” Briggs says. He also recognizes that tubing is a universal single-use component, …

Article Viral Clearance Challenges in Bioprocessing
Challenges remain for virus removal and validation. Nov 1, 2014 By: Cynthia Challener, PhD BioPharm International Volume 11, Issue 27, pp. 42-44 Removal and inactivation of adventitio…

Article Evaluating Design Margin, Edge of Failure and Process
Design space generation is encouraged in new product development. Sep 1, 2014 By: Thomas A. Little, PhD BioPharm International Volume 27, Issue 9, pp. 46-49 A product’s or proc…

Article Q&As with Industry Leaders
…;Strategic Technology Partnerships Leader, Cytiva What's in Your Media? How Costly is Variability of Cell Culture Media to Your Manufacturing Process? Megan Manzano, BioPharm Interna…

Article Monoclonal Antibodies Key to Unlocking the Biosimilars Market
The biosimilars market, many analysts believe, is on the cusp of significant growth. This growth in large part is due to the fact that numerous monoclonal antibody (mAb) biosimilars are expect…

Article Quality by Design—Bridging the Gap between Concept and Implementation
The drive to embed quality-by-design (QbD) principles into the pharmaceutical regulatory framework of the European Union has reached a key point 10 years after the European Medicines Agency (EMA) firs…

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