Search results for "chromatography"
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How to program, run and evaluate a design of experiments (DoE)
Martin Sichting, Product Manager Lab Scale Chromatography Systems at Cytiva, guides you through the DoE process.
You’ll learn how to program, run, and evaluate a design of experiments (DoE) run. An…
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On-demand: ÄKTA process™ system virtual demo
In this virtual workshop Torbjörn Blank will explain how the ÄKTA process™ chromatography system has been updated and how it compares to its predecessor. Linus Holmestrand will join us from our s…
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Announcing ÄKTA ready™ extended single-use system
ÄKTA ready™ extended system is a single-use liquid chromatography system designed for process scale-up and GMP manufacturing.
The system uses disposable flow paths and prepacked …
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How to Use Multiwell Plates With Manual Operation
High-throughput tools like PreDictor™ plates prefilled with chromatography resins make it possible to explore a large characterized space for optimizing process conditions. They save time and require …
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Top Process Development Trends for 2022 and a Look into 2023
The article, “Next-generation Protein L Chromatography,” for example, begins by establishing that the diversity of antibody variants in today’s pipeline presents unique challenges for purification pro…
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Good Modeling Practice
Mechanistic models have become a very promising technique to describe chromatography processes. These models offer numerous advantages such as cost and time reduction and are applicable at any point o…
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Optimization of a HIC step for recombinant protein purification
Follow this step-by-step high-throughput process development (HTPD) workflow to determine the optimal resin and initial conditions for hydrophobic interaction chromatography (HIC).
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Quality by design in biotherapeutics purification white paper
Learn how understanding and addressing variability sources can help you develop robust chromatography processes. The principles and methodologies of biopharmaceutical manufacturing are well …
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Alkaline stability of Fc and VH3 binding in protein A resins
In the development of antibody purification protocols, you need to know your Ab molecule and its possible affinity binding sites for the chromatography resins. In this study, we have looked at…
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Tools and methodologies for smarter downstream process development
In this video, John Scibetta, Advanced Chromatography Specialist at Cytiva, is interviewed by BioPharm International and answers the following questions:
What do we mean when we say “Smar…