Search results for "chromatography"
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Optimizing capture and polishing steps in an rAAV purification process
The chromatography purification described includes affinity capture to maximize recovery with efficient impurity removal.
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Optimization of a Two-Step Purification Method for Bispecific Antibodies
Alligator Bioscience AB develops antibody-based pharmaceuticals for cancer treatment, specializing in mono- and bispecific antibodies for tumor-directed immunotherapies. Alligator and Cytiva devel…
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Mechanistic Modeling Resource Hub
Whether you’re planning experiments, looking for tools, or just curious about mechanistic modeling of chromatography, use this resource hub to stay informed and on track.
Learn more on mec…
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Explore the Process Intensifier App
• Downstream capture (protein A step) operations: explore the possibilities of high-capacity resins, Fibro rapid cycling, and continuous multicolumn chromatography.
• Both as a connected operati…
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Getting Started with Fibro PrismA - Free e-Learning
Fibro PrismA units for rapid cycling chromatography connect to ÄKTA™ systems in the same way. Additionally, you can use the same buffers.
Webcast
A route to deeper process understanding-Studying resin variability using a Process Characterization
Chromatography resin attributes can affect critical quality attributes (CQAs) as well as process performance depending on the process design and the separation at hand.
Ligand density is an important…
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Evaluation of Fibro PrismA for Scalable Single-Use mAb Purification
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In clinical monoclonal antibody (mAb) manufacturing, capture on protein A chromatography resin gives excellent recovery and purity. However, because clinical batch siz…
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Sanitization Opportunities for Protein A Resins
Several protein-based chromatography resins are also sensitive to such harsh sanitization conditions. As an alternative, the oxidizing agent peracetic acid (PAA) could be used in the control of such c…
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Recent Development in Fibro Technology
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Fibro technology enables rapid cycling chromatography to accelerate research and process development, as well as increased productivity in large-scale manufacturing. T…
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Purifying Tagged Proteins: Learn the Basics
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What is tagged protein purification? When and why should you use it? Learn the basics in our quick guide to tagged protein purification.