Search results for "chromatography"
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Raw Material Variability: The Need for Deeper Process Understanding
The focus lies on chromatography resins.
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Design Considerations for a Commercial Cell and Gene Therapy Facility
…l therapy production) and characterized by larger single-use bioreactor skids with large downstream chromatography platforms, often segregated into two or more rooms. In mAb production, Chinese hamst…
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Ensure SEC Column Reproducibility in Protein Drug Analysis
Size exclusion chromatography (SEC) is the go-to analytical method in the analysis of therapeutic protein drugs. This article describes the factors affecting the reproducibility of columns and how you…
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How Coupling MALS to IEX Can Help Protein Characterization
Coupling ion exchange chromatography (IEX) to multi-angle light scattering (MALS) can open new opportunities in protein characterization. Mario Lebendiker and Hadar Amartely from The Hebrew University…
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Process Economy Simulations on a Protein A Capture Step
MabSelect PrismA is a next‐generation protein A chromatography resin that offers significantly enhanced alkaline stability and capacity compared with its predecessor products. This application note …
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Your Source of Information for Automated Multistep Protein Purification
Increasing the level of automation in protein purification can free up time and allow other tasks to be performed while the chromatography system is working. Cytiva has gathered recourses to support a…
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State of the Biopharmaceutical Industry: Lessons from 2018 Survey Data
Bioprocessing professionals expect continuous processing to be soon become a reality, particularly advances in continuous chromatography. But with related new equipment and technologies just coming to…
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Combining Purification Techniques in a Multistep Approach
In this blog post, learn how to select and combine purification techniques to successfully run your multistep chromatography scheme.
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A Look into the Future of Biopharmaceutical Quality
Many monographs utilize traditional high-performance liquid chromatography (HPLC) for testing. Companies have migrated to ultra-high-pressure liquid chromatography (UHPLC) and other sophisticated meth…
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Selection Guide: Columns and Resins for Antibody Purification and Immunoprecipitation
Polyclonal antibodies, monoclonal antibodies (mAbs), and antibody fragments are usually purified by affinity chromatography. Resins containing an immobilized ligand (e.g., protein A, protein G, or p…