Search results for "chromatography"
Article
Quality by design for biotechnology products—part 1
…pplements such as protein hydrolysates, and components such as nucleases or residual Protein A from chromatography resins used in the purification process.
There are multiple approaches to assess…
Article
Reviewing the Importance of Biosimilarity and Interchangeability
Techniques [such as] mass spectrometry, chromatography, spectroscopy, and electrophoresis are commonly used for this purpose,” Stamm says.
The biological activity of the biosimilar should also be …
Article
Free handbook for column packing and maintenance
Does large-scale column packing seem daunting? Impossible to get right? This new handbook can help! Packed with valuable guidance for using AxiChrom™, BPG and Chromaflow™ columns, you’ll disco…
Article
Buffer optimization for separation of bsAb in a capture step using MabSelect™ VL resin
Protein L resins bind to kappa light chain and are often used to purify antibody fragments such as dAbs and Fabs — but they can also be used to remove product-related impurities from bispecif…
Article
Downstream Process Developers: What are Your Antibody Processing Challenges?
Process developers, we want to hear from you! We're asking PD scientists to tell us about their biggest challenges developing downstream processes for mAbs and their variants.
Take this …
Webcast
Webinar: Building an Innovative Integrated Continuous Downstream Manufacturing Platform for the Production of Biologics
It involves dealing with variable perfusion flow rate, normalization of dynamic perfusion titer profile, sizing between intermittent (bind-elute chromatography) and continuous (viral inactivation) uni…
Article
Explore ÄKTA pilot 600 in 3D
Cost and speed are critical components in biomanufacturing. See how ÄKTA pilot™ 600 supports scale-up from process development to GMP clinical scale.
Explore this ÄKTA™ system in…
Article
Guide for selecting affinity resins for mAbs, bsAbs, and antibody fragments
Development of antibody-derived molecules are increasing. Today, molecules such as bispecific antibody (bsAb) and antibody fragments such as Fab, scFv, and VHH are seen in labs all over the w…
Webcast
PREP 2024
36th International Symposium on Preparative and Process Chromatography
May 28-31, 2024
Philadelphia, PA
Article
Save the date for HTPD 2025
We are pleased to announce the 7th International Conference devoted to High-Throughput Process Development (HTPD) and smart PD, to be held May 26–29 2025 in Uppsala, Sweden.
The program and…