Search results for " process"
Article
Quality Considerations for Using AI in Bio/Pharma
But does the regulated nature of bio/pharmaceutical development, manufacturing, and commercialization serve up unique challenges for incorporating AI into processes? According to Siegfried Schmitt, vi…
Article
Reviewing the Importance of Biosimilarity and Interchangeability
Identifying and quantifying impurities should include process-related impurities, degradation products, and contaminants. This is a crucial aspect of biosimilar development, Stamm notes. “Analytical m…
Article
Introducing Supor Prime Filters: A Filtration Solution for High-Concentration Therapies
It is harder to process fluid through the filter and it clogs faster. Manufacturers are compensating for this with oversized filters that have more hold-up. In a highly concentrated drug, every drop c…
Article
Extractables in Single-Use Systems Used in ADC Manufacturing, Part 2
The low levels of extractables found in this study support the use of ReadyToProcess™ columns, ÄKTA readyflux™ flow kits, and ÄKTA ready™ flow kits in ADC processes.
Read the application …
Webcast
Webinar: Intensifying Downstream Bioprocessing With Continuous Technologies
In this webinar we will explore common bottlenecks in downstream processing and look at continuous processing solutions that can further intensify the monoclonal antibody (mAb) platform.
We will di…
Article
Alternative solutions to separate AAV full and empty capsids using anion exchange
Key for a successful process are high overall yields of full capsids with effective empty capsid reduction and efficient impurity removal.
Here we present high-performance anion exchange (AEX) chr…
Article
Exosome isolation by tangential flow filtration and size exclusion chromatography
We demonstrate a scalable workflow for the isolation of exosomes—a type of extracellular vesicle with significant potential for targeted drug/gene delivery. For research and development and di…
Article
Bracing for a Future Wave of Advanced Therapies
With the help of recent investor interest, progression of advanced therapy medicinal products (ATMPs) in the clinical space continues to move forward. Buoyed by the regulatory approval of sever…
Article
Selecting Chromatography Resins for Bispecific Antibody Purification
Targeting enhancement with two active antibody arms makes bispecific antibodies (bsAbs) highly attractive for the treatment of cancer and other diseases. Their purification can be more challen…
Article
Chromatography innovations for the diversified antibody pipeline
Introducing MabSelect™ VH3 affinity resin for antibody variants
At Cytiva, we connect with process developers and manufacturers to understand their needs and strive to make t…