Search results for " process" in Articles / App Notes
Article
How to Use Multiwell Plates With Manual Operation
FDA initiatives such as quality by design (QbD) put demands on better process understanding. High-throughput tools like PreDictor™ plates prefilled with chromatography resins make it possible to explo…
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Efficient chromatography buffer prep with inline dilution
We also compare the process economy of ILD versus manual buffer preparation — which is still the most common way to prepare buffers — by looking at the labor time, buffer volumes, floor space, and req…
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New hydrophobic interaction chromatography (HIC) handbook
Hydrophobic interaction chromatography (HIC) separates biomolecules under mild conditions according to differences in molecular hydrophobicity. HIC is often used as a next step to purify prote…
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Take part of the Southeast Asia BioChallenge
Looking to create the next breakthrough innovation? Cytiva is here to support you to bring your molecule to market in the shortest possible time. By applying to our BioChallenge, you stand …
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Do Modeling and Simulation Tools Really Benefit the Biosimilar Industry?
The business impact of modeling and simulation tools is not well understood and requires clarification of their benefits to drug development.
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Rethinking ion exchange chromatography modeling
In the early days of modeling, mechanistic models for ion exchange chromatography were mostly based on stoichiometric equations. A new adsorption isotherm class was introduced in 2021: the co…
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Engage a mechanistic modeling expert – or become one
The application of mechanistic modeling requires expertise for effective use. When planning to implement this ground-breaking technology one essential question must be addressed befor…
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Adsorption isotherm models for chromatography
Read on commonly used models for the thermodynamics of adsorption within a chromatography column.
Indeed, in order to create a complete chromatography model, the adsorption of compon…
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Understanding fluid dynamics within a chromatography column
See how fluid flow effects within a chromatography column are used by mechanistic models.
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Mechanistic chromatography modeling in practice
Access insider recommendations for getting started with mechanistic modeling of chromatography, but also case studies and scientific publications.
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