Search results for " process" in Articles / App Notes
Article
Exosome isolation by tangential flow filtration and size exclusion chromatography
We demonstrate a scalable workflow for the isolation of exosomes—a type of extracellular vesicle with significant potential for targeted drug/gene delivery. For research and development and di…
Article
Bracing for a Future Wave of Advanced Therapies
With the help of recent investor interest, progression of advanced therapy medicinal products (ATMPs) in the clinical space continues to move forward. Buoyed by the regulatory approval of sever…
Article
Selecting Chromatography Resins for Bispecific Antibody Purification
Targeting enhancement with two active antibody arms makes bispecific antibodies (bsAbs) highly attractive for the treatment of cancer and other diseases. Their purification can be more challen…
Article
Chromatography innovations for the diversified antibody pipeline
Introducing MabSelect™ VH3 affinity resin for antibody variants
At Cytiva, we connect with process developers and manufacturers to understand their needs and strive to make t…
Article
Interactive eBook - Understand and unlock the potential of digital scaling
Explore the possibilities with a digital process to reduce time and costs associated with your operations. Get started by downloading our free eBook.
DOWNLOAD EBOOK
Article
Good modeling practice: workflow and case study
Learn more about a recommended mechanistic modeling workflow for successful in silico chromatography process development. The workflow is illustrated with examples from a modeling case study a…
Article
Host cell protein quantitation using ELISA
Host cell proteins (HCPs) produced by cells during biologic manufacturing must be removed from the final product to protect patients. However, it’s challenging to detect HCP, and this step c…
Article
Get a strong start in oligonucleotide manufacturing
How can you harness their full potential? When starting process development, you need to know where to focus, and you need a scalable and flexible solution. Building on 40 years of experience, Cytiva …
Article
Antibody purification quiz
How well do you know antibodies and antibody purification?
Test your knowledge and gain insights in the purification of antibody variants – bsAbs, Fab, dAbs.
Article
Developing a HIC polishing step for removal of mAb aggregates
This article describes the development of a flow-through (FT) polishing step using hydrophobic interaction chromatography (HIC) to remove mAb aggregates.
It includes:
- The use of HTPD plate…