Search results for " process" in Articles / App Notes
Article
Cell-free Expression Systems Pose Cell Culture Alternative
One approach that potentially offers the benefit of a “cleaner” biologic product in upstream processing is the use of cell-free expression systems. By producing less waste upstream, there is the poten…
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Boost Performance with a Chromatography Resin Update
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As protein purification has evolved and new molecule types have come to the forefront, scientists in process development and biomanufacturing have grown to expect ever-higher…
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Strategies and Emerging Technologies for mAb Capture
Strategies will depend on the mode of upstream operations (fed batch or perfusion) and the desired process improvement of the capture step, (e.g., productivity, cost, or process time) as well as the t…
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Virus-like Particles as Therapeutic Moieties of the Future
These biophysical, biochemical, and immunochemical methods ensure process reproducibility and product consistency in recombinant VLPs during the manufacturing process. These characterization methods a…
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Innovations in Cell Culture: Developing the Future
Join this discussion to explore the costs versus benefits of selecting certain cell culture process development innovations.
Innovations is a new virtual series from Cytiva exploring the nee…
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Pairing Data Connectivity and Comprehensive Automation
In the biopharma industry, process data are used in many ways throughout process development and the different production phases. Learn more about Cytiva’s automation solutions for bioprocessing, ce…
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Five Control Strategy Options to Prevent Resin Variability Impact
Here are the pros and cons of five control strategies that can provide process consistency even in the presence of chromatography resin variability.
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Scalable ADCF Virus Production Using HyClone™ VaccineXpress Medium
The results were used for scaling up the process to a ReadyToProcess WAVE 25 bioreactor system at a 2-L working volume. The data show that the ADCF process using VaccineXpress for rotavirus propagatio…
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Collaborative PD Outsourcing: Why Closer is Better
Sharing process details externally might seem too close for comfort, but when it comes to process development (PD) outsourcing, a close collaboration can actually bring added benefits.
Cl…
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Efficient and Scalable Buffer Preparation
This article describes how to ensure a scalable process for buffer management from process development to manufacturing with inline conditioning (IC). It also explains how Ä…