Search results for " process" in Articles / App Notes
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High-concentration monoclonal antibody drugs: manufacturing challenges
Solutions that maintain quality, maximize process yield and product recovery are available and can be introduced to adapt an existing manufacturing platform to the new process requirements.
Downloa…
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A risk based approach to sterile filtration
Process validation is required to establish scientific evidence that a process is capable of delivering an effective and safe drug consistently and reproducibly.
Download the white paper to learn …
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Xcellerex™ X-platform bioreactor live virtual demo
We designed Xcellerex™ X-platform bioreactors to meet your process needs today and in the future. Whether in pilot or cGMP facilities, the modular and application-based approach improves cell …
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Optimization of a two-step purification method for bispecific antibodies
This presentation shows the results from Cytiva collaborating with Alligator to develop an efficient downstream purification process for a cancer immunotherapy bispecific antibody (bsAb). A two-step p…
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Protein L affinity resin is ready to move to manufacturing
This improvement could address existing protein L resin limitations in biomanufacturing processes.
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Dynamic Binding Capacity in Fiber-Based Chromatography
Just like with resins, the dynamic binding capacity (DBC) of a Fibro unit is affected by process conditions and by the properties of the target molecule. Thus, determining the DBC of a Fibro unit is s…
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mRNA: The Messenger - mRNA Synthesis
Join us for part 3 of mRNA: the messenger, where we discuss key considerations for the synthesis of RNA molecules, including optimizing the mRNA template design, in vitro transcription, and process pa…
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Principles of Cell Line Development
It also takes a closer look at where it fits into this wider process including:
Overall path to market
Key processes and methods
Tools and equipment
Key regulatory re…
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Improving the Oligonucleotide Synthesis Experience
Addressing this challenge was one of Cytiva’s main goals when we set out to develop a system for small-scale synthesis and process development.
>>> Watch the presentation
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Cell Culture Media Selection Guide for Your Lab Wall!
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Doing cell culture and upstream process development on antibodies, vaccines, or viruses? Then you’ll want this poster. It will help you select the right cell culture medi…