Search results for " Mabs"
Article
Use of Multivariate Data Analysis in Bioprocessing
Amanullah, mAbs, 2 (5), pp. 466-479 (September 2010).
2. A. S. Rathore and R. Mhatre, Eds., Quality by Design for Biopharmaceuticals (John Wiley & Sons, Hoboken, NJ, 2009).
3. A.S. Rathore, N.…
Article
Tackling Analytical Method Development for ADCs
“Traditional cysteine and lysine chemistry is still a significant part of the ADC regime, but we are seeing a greater breadth of linkers, toxins, mAbs, and classes of conjugation chemistry. New analyt…
Article
High-Throughput Process Development in an Historical Environment
Genentech is said to be working with less than 20 different formulations, developed mainly for mAbs, but these formulations have also been shown to work for other types of target molecules. Instead, t…
Article
Continued Process Verification for Biopharma Manufacturing
The authors discuss complications of implementing continued process verification and provide recommended approaches.
Oct 1, 2014
By: Jeff Fleming, Robin Payne
BioPharm International
…
Article
Concentrating Feed—an Applicable Approach to Improve Antibody Production
Kelley, mAbs. 1 (5) 443-452 (2009).
2. F. Li et al., mAbs. 2 (5) 466-479 (2010).
3. The Merck Index (Merck & Co. Inc., Whitehouse Station, NJ, 13th ed., 2001).
4. P. Hossler et al., Biotec…
Article
2014 Manufacturing Trends and Outlook
…ibodies (mAbs); more than 55% of those surveyed said they manufacture protein-based drugs other than mAbs. More than 40% of the respondents said their companies manufacture vaccines; 17.7% develop ce…
Article
Optimizing KiH bispecific antibody chromatography steps
… Cytiva developed an optimized capture step for two closely related knob-into-hole (KiH) bsAbs using MabSelect PrismA™ protein A resin which reached a purity of 94%. In addition, two flow-through pol…
Article
Selected courses from cell culture and downstream process development to scale-up and manufacturing
Develop your skills and those of your teams with training courses designed for researchers, process development scientists, engineers, and manufacturing operators.
Built upon our expertise…
Article
Buffer optimization for separation of bsAb in a capture step using MabSelect™ VL resin
… elution pH, resolution between hetero- and homodimers for bsAb’s, and removal of light chain from mAbs during elution when using MabSelect™ VL protein L resin. The video includes results of these ex…
Webcast
Webinar: Intensifying Downstream Bioprocessing With Continuous Technologies
Significant operational improvements can be achieved by intensified continuous processes compared to standard batch processes.
In this webinar we will explore common bottlenecks in downstream pr…