Search results for " resin" in Articles / App Notes
Article
Tips for Successful Immunoprecipitation
For immunoprecipitation (IP), there are four main components that you can control to get good results: protocol, resin, format, and antibody. Read these tips to get it right from the start.
Ac…
Article
Column Selection Guide for ÄKTA Systems
…hromatography Columns
Download the Selection Guide for Size Exclusion Chromatography Columns and Resins
Article
Asked and Answered: Your Questions on Ion-Exchange Chromatography
The questions are organized in by chief concern, and include buffers, experimental design, LC system and configuration, resin and column selection, specific applications, as well as troubleshooting an…
Article
Sources of Bioburden You Might Have Missed
A problem with traditional mAb manufacturing is that there are so many potential entry points for microbial contamination. There are, however, ways to shut the door on contamination.
The risk …
Article
HTPD: Optimizing a mAb Chromatography Polishing Step
In this webinar, a case study using high throughput process development tools, optimizing process conditions for a mAb polishing step using a multimodal chromatography resin (Capto MMC ImpRes), will b…
Article
Cost Considerations Drive Lean Technology in Biopharmaceutical Manufacturing
Nanofiber adsorbants are another resin column alternative. They are able to flow at fast rates, albeit with low binding capacity.
Taken together, upstream and downstream process innovations can be…
Article
Technical and Process Economical Aspects of Using Capto™ Q and ReadyToProcess™Adsorber Q in mAb Polishing
Here, we compare the performance of the disposable ReadyToProcess Adsorber Q membrane capsule with Capto Q resin packed in conventional chromatography columns when used in the final polishing step of …
Article
Efficient Purification of the Pertussis Antigens Toxin, Filamentous Haemagglutinin, and Pertactin in Chromatography Workflows
This application note describes the purification of pertussis toxin (PT), filamentous haemagglutinin (FHA), and pertactin (PRN) in a process based on modern chromatography resins. The described meth…
Article
Safety Drives Innovation in Animal-Component-Free Cell-Culture Media Technology
Advances in cell culture media technology have helped achieve safer biologics.
By Tom Fletcher, Holden Harris
Regulatory expectations for cell-culture-based biologics production processes ch…
Article
Single-use technologies in downstream process intensification
In bioprocessing, thorough cleaning is critical in order to take full benefit of the resin by removing impurities. When using conventional chromatography solutions, cleaning and cleaning validation …