Search results for " regulators" in Articles / App Notes

Article Avoiding Investigational Failures and Discrepancies
Avoiding Investigational Failures and Discrepancies Investigational failures and discrepancies can be avoided through the proper execution and documentation of investigations. By Walt Murray,…

Article Best Practices for Data Integrity
Best Practices for Data Integrity Optimize practices and meet requirements using electronic data integrity systems. By Jennifer Markarian Maintainin…

Article Managing Residual Impurities During Downstream Processing
He adds that the use of commercial or platform assays early in development is common, but most regulators expect a well-qualified process-specific or platform assay for later development and post-appr…

Article Cost Considerations Drive Lean Technology in Biopharmaceutical Manufacturing
By Catherine Shaffer Four biosimilars have been approved for the market by FDA as of February 2017, and more are in the pipeline. Now that biosimilars are here to stay, manufacturers are devel…

Article Automating Processes in Upstream Processing
…d with process control systems, and the collection and the protection of these data is paramount for regulators. Proving data integrity is one of the most important aspects of any control system as t…

Article Advancing Single-Use Technology Through Collaboration
“We still need more three-way conversations between end users, suppliers, and regulators, so that we are all on the same page on the key challenges and mutual expectations, as well as the regulatory i…

Article Efforts Accelerate to Streamline Postapproval Change Process
FDA and other regulators have sought to address these issues by encouraging industry adoption of continual improvement and quality-by-design approaches, along with change management protocols and life…

Article What’s In a Name? For Biosimilars, A Lot
Jun 01, 2015 By Randi Hernandez BioPharm International Volume 28, Issue 6 There is still some uncertainty surrounding whether a biosimilar will share the same compendial identity—or …

Article Modern Manufacturing Systems Key to FDA Quality Initiative
Apr 02, 2015 By Jill Wechsler Pharmaceutical Technology Volume 39, Issue 4 To ensure patient access to high quality, safe, and effective medicines, FDA spends considerable time and resou…

Article The Bullish Outlook for Biosimilars
Feb 01, 2015 By Jill E. Sackman, PhD, Michael J. Kuchenreuther, PhD BioPharm International There are several important reasons for stakeholders to be optimistic about prospects for b…

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