Search results for " buffers"
Article
Improving mAb Manufacturing Productivity by Optimizing Buffer and Media Prep Process Flow
Solid or hydrated buffers and salts that come ready-to-dispense in single-use bags and buffer preparation using single-use systems, reactors, and in-line dilution can both help eliminate or reduce wei…
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Will My Buffers Work When Using an Inline Conditioning System?
In-line preparation of buffers from highly concentrated, single-component stock solutions saves both time and storage space. Compared with preparing one concentrate per buffer formulation, many differ…
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Make buffer preparation more time and cost efficient with inline conditioning
Preparation of these buffers is a challenge that in-line conditioning can overcome. Inline conditioning simplifies buffer preparation and offers significant reduction in number of tanks, buffer soluti…
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Efficient chromatography buffer prep with inline dilution
We also compare the process economy of ILD versus manual buffer preparation — which is still the most common way to prepare buffers — by looking at the labor time, buffer volumes, floor space, and req…
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Automated In-Line Buffer Preparation from Ready-Made Stock Solutions in a mAb Process Step
To further reduce the time and space required, ready-made stock solutions delivered in disposable bags were connected directly to the Inline Conditioning system and feedback regulation of the final bu…
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Overcoming Buffer Challenges With In-Line Conditioning
With IC, buffers of desired formulations are prepared from smallvolume single-component stock solutions at the time of need. Formulating buffers from single-component stock solutions eliminates the ne…
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Buffer Management Solutions for Large-Scale Biomanufacturing
Learn how different approaches can resolve buffer management challenges in large-scale biomanufacturing. This article discusses solutions such as inline conditioning, outsourcing buffer preparation,…
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Automated Buffer Preparation – Increasing Production Capacity While Maintaining Footprint
In fact, buffer preparation is known to be one of the most resource-intensive activities in biomanufacturing, as large volumes of buffers and process liquids are often required as production capacity …
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From Bottlenecks to Breakthroughs: Mastering Buffer Management
Agenda
- Options to intensify buffer preparation from using pre-made buffers or buffer concentrates to implementing inline dilution or inline conditioning.
- Considerations for calculating the…
Article
Can You Trust a Machine for Downstream Bioprocess Buffer Preparation?
There is a limit to how many stainless-steel tanks you can squeeze into a biomanufacturing facility. Still, resource-intensive buffer preparation has received little attention in biomanufacturing. S…