Search results for "Adaptation"
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Direct adaptation of adherent cell lines in classical media
Discover the options for direct adaptation of common adherent cell lines.
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How to Adapt Biomanufacturing Processes
As the need for more complex molecules drives a new era of biomanufacturing, there is an increased focus on developing processes with improved security, yield, and process economy. Companies working…
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Single-Use Chromatography: Adapting to Manufacturing Scale
Single-use technologies offer the flexibility needed to meet the demands of multiproduct facilities. The capital investment is lower, and substantial time savings can be made when eliminating cleani…
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What’s New in Upstream Technologies
Recent upstream processing innovations include enhanced sensor technology, single-use bioreactors, and automated cell culture systems.
By Amber Lowry
SCIENCE PHOTO - STOCK.A…
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Continuous Processing for the Production of Biopharmaceuticals
Path forward
While the adaptation of continuous manufacturing strategies in biologics may have been slow, the field is evolving. The significant benefits that continuous processing offers—includin…
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Commercial Production of Gene Therapies Using Suspension or Adherent Cell Lines
Cells used for gene therapy have not gone through this lengthy adaptation, which means that current suspension-adapted cell lines for the production or viral vectors still suffer from drawbacks as the…
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Advances in Sterilization Technologies for Overcoming Viral-Vector Manufacturing Challenges
Sterility must be assured for all biologic drug products. Terminal sterilization achieved via treatment with heat, radiation, or certain chemicals (vaporous hydrogen peroxide, vaporous peracet…
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Remote Monitoring and Big Data Advance Upstream Automation
Such innovations, Vann stresses, are critical to increasing digital maturity to the point where predictions can enable adaptation to inherent process variability so that consistent performance and qua…
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Use of Multivariate Data Analysis in Bioprocessing
Apr 06, 2015
By Anurag S. Rathore, Sumit K. Singh
BioPharm International
The ever increasing demand of biotherapeutics, together with the pressure to contain healthcare costs have motiva…
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Improving PAT for Biologics
He continues, “With standard adaptation via Ingold ports, compact and robust designs, and an attractive total cost of ownership, spectroscopy will become a standard tool for in-process monitoring and …