Search results for "pcc"
Poster
Scalable Continuous Chromatography Process for Enhanced Efficiency in Biomanufacturing
For continuous chromatography, interest in techniques such as periodic counter current chromatography (PCC) is increasing.
In this poster presented at the Recovery XVIII conference, based on dat…
Article
Continuous Processing for the Production of Biopharmaceuticals
For instance, in the case of chromatography, the available batch protocol can be run using periodic counter-current chromatography (PCC) with modification made to the process parameters to match the r…
Article
Maximize resin usage with continuous bioprocessing
Periodic counter-current chromatography (PCC) is a multi-step approach to maximize the chromatography resin capacity utilization and minimize process time. The technology employs three or more chromat…
Article
Continuous Chromatography: Trends, Definitions and Approaches
There is a lot of attention being paid to continuous chromatography, and several different terms are being used: SMB, PCC, MCC. What is your view on the terminology? Is there a difference among them? …
Article
Making the Move to Continuous Chromatography
There are several different techniques available, including simulated moving bed (SMB) and periodic counter current chromatography (PCC). The aim is the same for all: to achieve a continuous (over) lo…
Poster
Evaluation of Protein A resin lifetime during extensive use (overloading) in continuous chromatography mode
This application note compares the performance of MabSelect SuRe pcc resin designed for continuous capture of mAbs, with the conventional high-capacity Protein A resin MabSelect SuRe LX. The study was…
Poster
Integration of continuous upstream and downstream operations in mAb production
We describe the integration of a high-performing upstream cell culture process with downstream purification utilizing emerging technologies such as periodic counter-current (PCC) chromatography and st…
Poster
Continuous chromatography in downstream processing of a monoclonal antibody
In this study, periodic counter current (PCC) chromatography and straight-through processing (STP) technologies were evaluated in a continuous three-step monclonal antibody (MAb) purification proces…
Article
Technology Innovations Improve Process Chromatography Performance
Hardware innovations, such as simulated moving bed (SMB), periodic counter-current (PCC), or other systems, which allow users to make more efficient use of a resin are still emerging, he adds.
“We…
Article
Integrated Semi-Continuous Process for mAb Production
A complete process for the production of a biopharmaceutical consists of a great number of distinct unit operations, for example, cell culture, filtration, and chromatography. Linking these differen…