Search results for "sensor"
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Reconciling Sensor Communication Gaps
Process analytical technology (PAT), quality by design, and individual company- or process-centric quality initiatives are driving the development of bioprocess sensors and probes. Single-use systems …
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What’s New in Upstream Technologies
Single-use sensor and adapter
Emerson’s Rosemount 550pH sensor and Rosemount 550DW dissolved oxygen (DO) sensor adapter provide improved sensor stability for single-use bioreactors and are suited …
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Moving PAT from Concept to Reality
In-line sensors are placed in a process vessel or process stream to conduct the analysis in-situ. On-line sensors are connected to process side streams and perform periodic automatic sampling, returni…
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Real-Time Characterization of Biotherapeutics and Comparability of Biosimilars
In SPR, one of the interactants is immobilized to the sensor surface and the other is kept free in solution and passed over the surface. Association and dissociation are measured and displayed in the …
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Single-use Bioreactors Have Reached the Big Time
Significant advances in film technologies, bioreactor designs, stirring mechanisms, and sensor systems have contributed to the increasing adoption of disposable reactors from the lab to production sca…
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Achieving Process Balance with Perfusion Bioreactors
Equipment suppliers are responding to needs for more durable reactors and sensors, a greater variety of monitoring technologies, and bioreactors that can integrate with cell retention devices.
Per…
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Improving PAT for Biologics
Advances in high-throughput systems, Raman and near-infrared (NIR) spectroscopy, high-performance single-use sensors, and chemometric methods are also helping manufacturers of biopharmaceuticals overc…
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Improving Upstream Predictability
Some of the most significant gains have been made in cell line expression, advanced sensors, and automation, says Atul Mohindra, R&D director for biomanufacturing at Lonza Pharma and Biotech. “Using a…
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Automating Bioprocesses
For example, tubing sets typically are supplied gamma-irradiated by a third party, and sensors are typically pre-calibrated and gamma irradiated. All this additional information needs to be part of th…
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Digitalization: The Route to Biopharma 4.0
The equipment can be interfaced with the corresponding digital twins using sensors and actuators such that the real time data is fed to the digital twins and the in silico predicted can be employed fo…