Rapid Process Development of a CIEX Step for a Bio

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November 2, 2017 -

Sushma Nayak Teichert, Anna Maria Gudmundsdottir,

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When establishing purification processes for a biosimilar molecule it is important to develop steps that are scalable, selective, and c

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Repurposing Fed-Batch Media and Feeds for Highly P

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October 19, 2017 -

Andreas Castan, Eric Fäldt, Audrey Vuillemez, Wil

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The authors developed a method for identifying first-generation perfusion culture media based on existing fed-batch media and feeds. Here, t

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A Next Generation Protein A Chromatography Resin f

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October 5, 2017 -

David Westman, Annika Forss, Gustav Rodrigo, Thoma

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mAb production using a Protein A capture step has followed a highly successful synergistic path the last 30 years. There are, however,

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Impact of sporicidal agent on MabSelect SuReâ„¢ pr

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June 28, 2017 - Cytiva

Bacterial endospore contamination constitutes a challenge in bioproduction due to their resistance to high concentrations of NaOH, comm

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Strategies for optimized cell culture media: Effec

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June 14, 2017 - EmmaLee Garner, Kalle Johnson, Mark Wight

Effective biopharmaceutical production is achieved in part through target-specific, quality-optimized cell culture media. Balancing the

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Development of DoE based fed-batch strategies for

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June 14, 2017 -

David Reinhart, Andreas Castan, Lukas Damjanovic,

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Fed-batch culture is commonly employed to maximize cell and product concentrations in upstream mammalian cell culture processes. Typica

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Adenovirus production in a single-use stirring tan

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June 6, 2017 -

Teres Persson, Gustaf Ahlén, Susanne Stier, Mia B

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Adenovirus vectors are attractive delivery systems for vaccines and cancer treatment. Scalable and cost-efficient production technologi

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Case Study: Improve Process Economy by Cycling of

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May 31, 2017 - Cytiva

The use of disposable technologies in downstream processing has increased significantly over the last years, as they reduce the need fo

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Fast Trak Services: a collaborative project to acc

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May 18, 2017 - Cytiva

Biosimilars represent an innovative solution that can benefit both patients and healthcare systems  by reducing the burden of rising tr

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Resin selection to optimize the flexural strength

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May 4, 2017 - Cytiva, Sealed Air Corp.

Single-use bioprocess technology offers several advantages for manufacturing biopharmaceuticals, such as increased transportability of

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