Improve operational efficiency in biomanufacturing


October 11, 2016 - Cytiva

In the biopharmaceutical industry, process data is used in multiple ways throughout process development and the different production ph

Scale-up of CHO fed-batch cultures in HyCloneâ„¢ A


October 11, 2016 - Cytiva

Comparing cell growth and recombinant protein production of multiple Chinese hamster ovary (CHO) cell clones when cultured in HyClone A

Residual DNA analysis in influenza vaccine process


August 13, 2016 -

Camilla Estmer Nilsson, Hanna Kraft, Christine Sun

In cell-based influenza vaccine production, the European Pharmacopoeia demands a host cell residual DNA concentration of less than 10 n

Columns up to 1600 mm in diameter packed with prot


August 13, 2016 -

Johan Avallin, Anders Nilsson, Magnus Asplund, Nik

Axial compression allows for optimally packed beds also in the large-scale chromatography column range. Different methods have been dev

Process economy effects of modernizations in vacci


June 29, 2016 - Mia Bennemo, Anna Akerblom, Mats Lundgren

The vaccine industry is currently considering modernization of old, legacy processes. Old purification steps are being made obsolete by

Unlocking the potential for efficiency in downstre


May 25, 2016 - Cytiva

In today's bioprocessing industry, there is a demand to cut manufacturing costs while maintaining product safety and quality. Additiona

Integration of continuous upstream and downstream


May 25, 2016 -

Andreas Castan, Thomas Falkman, Eric Faldt, and An

Process intensification is gaining interest as a strategy to reduce production costs, while improving product quality and throughput in

Modes of controlling charge variant distribution i


March 30, 2016 - Cytiva

The characteristics of a biological drug, for example, charge variant profile, are determined to a large extent by the upstream express

Biacoreâ„¢ systems in vaccine development and prod


March 3, 2016 - Cytiva

The growing public awareness of a potential pandemic requiring rapid treatment of millions of healthy individuals has spurred renewed i

Optimizing productivity on high capacity protein A


February 5, 2016 - Cytiva

MabSelect SuReâ„¢ protein A affinity medium has long been considered a starndard tool for capturing monoclonal antibodies in biopharmac

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