Search results for " purification"
Poster
Residual DNA analysis in influenza vaccine processing
Samples from the vaccine purification process contain different buffers, salts, and host cell compounds, and varies 3–4 logs in DNA concentration from harvest to the final product, which all put strai…
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Affinity chromatography Handbook - Vol. 3: Specific Groups of Biomolecules
This volume of the Affinity Handbook describes the role of AC in the purification of specific groups of biomolecules, the principle of the technique, the chromatography media available and how to sele…
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Connect Alias™ Autosampler to ÄKTA™ Pure or ÄKTA Avant
When working with a large number of small volume samples, sample injection into your protein purification system can be tedious and time consuming. To minimize manual injections and save time, an auto…
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Affinity Chromatography Handbook: Vol. 1 Antibodies
The purpose of this handbook is to present the most effective and most frequently used strategies for sample preparation and purification of the many different forms of antibodies and antibody fragmen…
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Use of Multivariate Data Analysis in Bioprocessing
Single ultraviolet absorbance is routinely used for monitoring protein purification process. With the aim to develop a simple, fast and cost-effective methodology for protein quantification, researche…
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Detecting Protein Aggregates and Evaluating their Immunogenicity
Protein aggregation can occur during all stages of the lifetime of a protein therapeutic, including expression, refolding, purification, sterilization, shipping, storage, and delivery processes (1). T…
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2014 Manufacturing Trends and Outlook
Facilities that manufacture protein-based drugs reported use of multiple purification technologies. Ion-exchange chromatography was the most frequently reported (71.6%) followed by chromatography with…
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Supplier-Change Management for Drug-Product Manufacturers
Pharmaceutical change management processes extend to the materials and services employed to manufacture and test drug products, necessitating the need for an effective supplier-initiated change …
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PDA's Technical Report for Biotech Cleaning Validation
The authors encourage biotech manufacturers to consult PDA Technical Report No. 49 for a detailed perspective on current practices and issues in biotech cleaning validation.
By Anurag S. Rathore, D…
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Free handbook for column packing and maintenance
Does large-scale column packing seem daunting? Impossible to get right? This new handbook can help! Packed with valuable guidance for using AxiChrom™, BPG and Chromaflow™ columns, you’ll disco…