Search results for " surfac" in Articles / App Notes
Article
Gene Therapies Push Viral Vector Production
Infectivity, he explains, is usually dictated by the envelope proteins present in a virus and the cellular surface components to which those proteins bind. “Depending on the application, the ideal vec…
Article
New Therapies Present Scaling Challenges
In the roller bottle process, cells grow and attach to the surface of cylindrical bottles and are bathed in growth media as the bottle is rolled on a rack inside a temperature-controlled chamber. To i…
Article
Moving PAT from Concept to Reality
…n evaluation; next-generation sequencing (NGS) for viral and microbial contamination quantification; surface plasmon resonance, amplified luminescent proximity homogeneous assay, and fluorescence res…
Article
Faster Flavivirus Vaccine Production
Viral vaccines need to be produced fast and in large quantities. Routine immunizations and preventive campaigns, like stockpiling in response to emergencies, involve millions of doses, and speed is es…
Article
Webinar On-Demand: Novel Analytics to Improve Bioprocessing and Validation Guideline
He also covered the latest regulatory strategies and a new assay validation guideline for surface plasmon resonance (SPR) technology.
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Article
Leveraging Computational Models of Glycosylation for Biopharma QA
Examples of statistical models of TGP glycosylation are design of experiment (DoE) surface response models (23) and partial least squares regression (33,34). Advantages of statistical models are that …
Article
Are You in Control of the Quality of Your mAbs?
Stuart Knowling from Antibody Analytics presented how the latest innovation in surface plasmon resonance (SPR) technology has been adopted to develop and qualify assays for monoclonal antibodies (mAbs…
Article
Sensitive and Reproducible SPR-Based Concentration and Ligand-Binding Analyses
Surface plasmon resonance (SPR) assays are used across the life cycle of a biopharmaceutical, from target identification, through CQA determination, development, and on-going quality control. This art…
Article
Nurturing Knowledge from Disparate Data Streams
Similarly, the volume of data generated in NMR and surface plasmon resonance analyses can be challenging to manage.
Issues with data abstraction
Another challenge given the volume and c…
Article
Make the Switch from ELISA to Biacore™ SPR-Based Assays Today
General guidance on how to convert an existing ELISA assay to a Biacore surface plasmon resonance (SPR) assay and how, by doing so, you can get results in less than half the time compared with ELISA. …