Search results for " recombinant"
Article
Single-use Bioreactors Have Reached the Big Time
“[Cytiva] is taking its experience in single-use bioreactor technologies for monoclonal antibody, recombinant protein, and vaccine processes and applying it in our Xuri line of cell therapy equipment …
Poster
Effects of feeding strategy on CHO cell performance in fed-batch cultures
ActiPro cell culture production medium is intended to be used in combination with Cell Boost 7a and 7b supplements to enhance recombinant protein production in fed-batch or perfusion processes. This…
Article
Biopharma in 2016: Higher Quality Drugs, Less Expensive Manufacturing
…ologies in Downstream Process Intensification
A Risk-Based Genetic Characterization Strategy for Recombinant CHO Cell Lines Used for Clinical and Commercial Applications
A Second Modular Bi…
Article
Improving Process-Scale Chromatography
She points to several new types of affinity chromatography resins introduced to the market in recent years that target recombinant plasma proteins, gene therapy applications, and different types of an…
Article
Process Chromatography Selection for Downstream Processing Applications
…
Björkman (Cytiva): If one excludes mAbs, then the molecules of interest are generally peptides, recombinant proteins, or vaccines. For these molecules, chromatographic techniques such as ion-exch…
Article
Perfusion in the 21st Century
By the early 2000s, perfusion was largely used to manufacture only products such as recombinant blood-clotting factors and enzyme treatments for rare metabolic storage disorders such as Fabry’s diseas…
Article
Generating a Fully Processed Antibody
Protein conversion by FGE
Figure 1: Formylglycine-generating enzyme (FGE) protein recognition site and conversion process in the context of a recombinant protein of interest.
Formylglycine-gene…
Article
Affinity Chromatography Handbook: Vol. 1 Antibodies
The use of recombinant technology opens up the potential to create an infinite number of combinations between immunoglobulins, immunoglobulin fragments, tags and selected proteins, further manipulatin…
Article
A Platform Approach for the Identity Testing of Multi-Component Cell-Culture Media
…omponents of cell-culture media used in a Chinese hamster ovary (CHO) cell manufacturing process for recombinant proteins (11). Although, both NIR and Raman spectroscopy are fast and non-destructive,…
Article
Designing a Biomanufacturing Facility Incorporating Single-Use Technologies
Will the facility be manufacturing monoclonal antibodies, recombinant proteins, vaccines, antibody-drug conjugates, or fragment antibodies? Also, will the products be mammalian cell-derived or microbi…