Search results for "PAT"
Article
Moving PAT from Concept to Reality
PAT is not only enabling, but essential, to continuous bioprocessing. With sufficient advances, emerging PAT solutions should ultimately make real-time release testing possible.
In-line, at-line, …
Article
Improving PAT for Biologics
…D) approach to pharmaceutical manufacturing is the implementation of process analytical technology (PAT) for ongoing monitoring and adjustment of production processes to ensure the production of biol…
Article
QbD and PAT in Upstream and Downstream Processing
Some of these CQAs, such as glycoxylation pattern for monoclonal antibody (mAb) products, are primarily impacted by the upstream process and are particularly important to monitor during process develo…
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The Importance of Process Intensification and PAT for Achieving Real-Time Release
Those process analytical technologies (PAT) are a critical part of control strategies that ensure continuous operation within the design space.
While …
Article
Leveraging Data for Better Biopharmaceutical Process Control
For many years, though, extending this approach into true process analytical technology (PAT) and using it to track and control processes was done mainly in the research lab.
Recently, there ha…
Article
The Lifecycle Change of Process Validation and Analytical Testing
Jones (Innopharma Labs): A manufacturer can only truly understand their process and successfully demonstrate continued process verification through the implementation of process analytical testing (PA…
Article
Remote Monitoring and Big Data Advance Upstream Automation
“Connected, continuous, and process analytical technology (PAT) solutions that bring more process intelligence and quality decisions to the factory floor are becoming more common,” asserts Marc Sincla…
Article
Analytical Considerations for Successful Upstream Process Development with Spivey and Lane
…ell perfusion
7:16 - Critical process parameters and CQA
9:25 - PAT
10:35 - Continuous manufacturing
Transcript
BioPharm Internatio…
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Digitalization: The Route to Biopharma 4.0
By transforming data into an intelligence-supporting decision-making tool, it is easy to realize the longstanding regulatory initiatives of process analytical technology (PAT) and quality by design (Q…
Article
Single-Use Technologies Prove Effective for Viral Vector Process Development
For single-use systems in particular, Sanderson adds that cell-culture compatibility is critical because many of the plastics and polymers used in biologics manufacturing are not inert to biological p…