Search results for " design" in Articles / App Notes
Article
Vaccine Development Faces Urgency and Challenges
Experts seek to improve public health infrastructure and to reach global agreement on clinical trial design and regulatory decision making to support rapid development of needed therapies. At a Minist…
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Lessons Learned Accelerate Vaccine Development
The company was able to rapidly evaluate the design space of the process and identify critical process parameters due to its extensive knowledge of its AdVac (adeno virus) and PER.C6 platform technolo…
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Continuous Processing for the Production of Biopharmaceuticals
Multiple tools are now available to design a continuous process, and researchers have demonstrated the tools’ successful use in a large variety of applications.
Table I: Summary of recent e…
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Adherent Cell Culture in Biopharmaceutical Applications: The Cell-Detachment Challenge
Reusability of culture substrates
Some responsive substrates designed to promote cell detachment under the effect of a particular stimulus undergo an irreversible structural modification that prev…
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Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
SPR analysis is widely used in research where antibodies are either designed for improved interaction with Fc-γ receptors (29) or for the elimination of immune effector functions when non-immunostimul…
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Trends in Single-use Bioreactors
In addition, there are new systems now specifically designed for microbial fermentation.
Ang (Eppendorf): Most notable is the innovation of single-use bioreactors suitable for microbial fermenta…
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Optimizing Resin Performance with Disposable Chromatography Solutions
There have not been any major technical changes in the chromatography systems or columns design; however, we are seeing continuous improvement in associated sensor performance, accuracy, reliability, …
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Analyzing Proteins Using SEC, MALS, and UHPLC
Smaller flow cells and improved cell design, for example, have made it possible to connect more detectors together without the negative consequences of significant peak broadening and tailing. “As a …
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Novel Vaccine Technologies Meet the Need for Pandemic and Therapeutic Solutions
The company received FDA approval for Flucelvax, the first cell-culture vaccine in the US designed to protect against seasonal influenza in individuals 18 years of age and older, in November 2012 and …
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Monoclonal Antibodies Key to Unlocking the Biosimilars Market
…ry and higher-order structures, animal models, simulation tools and complex algorithms, expertise in designing clinical trials that target the appropriate end points and do so with as few patients an…