Search results for " design" in Articles / App Notes
Article
3rd BioProcessing Asia Preview: Q&A with John Curling
…;Plasma product biotechnology: the changing environment
• Theory and practice of facility design, process economics and lean manufacture
Unlike many other conferences. BPA invites the submiss…
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Process Development: What May Lie Ahead in 2018?
Single-use bioreactors, for instance, are increasingly available from a host of vendors, and suppliers of such technology have made “significant advances in film technologies, bioreactor designs, stir…
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Reliability Rooms and the Move to Proactive Supply Chain Management
These centers are designed to analyze data and provide insights for production forecasts, identify planning and risk metrics, and predict trends and areas of improvement across all of the company’s su…
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Protein Purification Handbooks
Make sure you have the latest protein purification handbooks!
Whether you are a beginner or an expert, Cytiva handbooks provide practical tips and in-depth information about protein purif…
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Asked and Answered: Your Questions on Ion-Exchange Chromatography
The questions are organized in by chief concern, and include buffers, experimental design, LC system and configuration, resin and column selection, specific applications, as well as troubleshooting an…
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Unifying Continuous Biomanufacturing Operations
study was designed to run using primarily single-use, disposable materials. Of these materials, 95% of parts were gamma sterilized. There is difficulty associated with sterilizing chromatography colum…
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Extractables Studies for Single Use Systems Used in ADC Manufacturing, Part 1
The studies were designed to ensure that conditions were exaggerated compared to existing ADC manufacturing processes. Extractable organic compounds and trace elements from the single‑use components…
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Speed and Flexibility Are Dual Goals for Biopharma Operations
To expedite the review of new manufacturing technologies, FDA has initiated efforts to promote early discussion between drug sponsors and the agency to address manufacturing design and development iss…
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Efficient concentration of a low-titer bovine IgG with high recovery in low volume
This application note describes the design of circuits with low working volume, allowing for high concentration of dilute feed streams. The use of ReadyCircuit™ single-use assemblies allowed for as…
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Biopharma in 2016: Higher Quality Drugs, Less Expensive Manufacturing
…ze the Pharmaceutical Manufacturing Base, a product of the agency’s Emerging Technology Team (ETT) designed to help manufacturers implement a variety of technological advancements.3 This draft guidan…