Search results for " capacity" in Articles / App Notes
Article
Development and Future of Protein A Chromatography Technology: Q&A with Jonathan Royce, Business Leader Chromatography Resins, Cytiva
In the last decade, significant development has also been made in the area of Protein A, both in term of binding capacity and stability, as discussed in a previous Q&A session. What do you feel are th…
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Improvements in Protein A Chromatography
…lacing protein A chromatography step with alternative purification methods due to the high cost, low capacity and limited robustness of Protein A. However since 1978, the capacity and productivity of…
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Fluid Handling in Biopharma Facilities
On the other hand, readdressing fluid handling capacity and functionality within an existing facility can yield substantial operational and cost benefits. Here as well, conceptual work pertaining to p…
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Biomanufacturing Outsourcing Globalization Continues
…ary data from BioPlan Associates’ 12th Annual Report and Survey of Biopharmaceutical Manufacturing Capacity and Production (1).
As part of the survey, biotherapeutic developers are asked to estim…
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Application of Quality by Design to Viral Safety
…w the level of viral contaminants in process load materials can be compared with the viral reduction capacity of the manufacturing process so that an assessment of the level of viruses in a dose of p…
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FDA Seeks Metrics to Define Drug Quality
Boosting capacity
While manufacturers see value in quality metrics, they are less enthusiastic about proposals that FDA encourage redundant manufacturing sites as a strategy for preventing shortage…
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Report from the Eighth International Plasma Product Biotechnology Meeting Melia Salinas, Lanzarote, Spain
Key considerations such as LEAN, multipurpose and flexibility was designed and built in to the facility from start, ensuring high capacity, microbial control and tracing of all filled vials. During th…
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Flexibility in Biopharmaceutical Manufacturing
The ability to install capacity within a horizon of near certainty is a very valuable position to be in.
KEEPING UP WITH DEMAND
At plant level, capacity will have to be flexible not just to …
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Considerations in depth filter scale-up
The complex nature of the raw materials gives each filter a relatively broad pore size distribution and provides some adsorptive capacity through charge and hydrophobic interactions. The filter media …
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Evaluating the Use of Continuous Chromatography
…rations, continuous chromatography can offer significant productivity gains and increased production capacity, for example, through increased utilization of chromatography resin binding capacity, red…