Search results for " throughput"
Article
Reimagining Affordable Biosimilars
Nano differential scanning fluorimetry (nano-DSF) has emerged as a high throughput platform for screening biotherapeutic formulations. Light scattering tools permit label-free size characterization, t…
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Speeding Up mAb Purification Using Fiber-based Technology
Read more on high throughput automated mAb purification using HiTrap Fibro PrismA.
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Automation Trend in Fill/Finish Reduces Contamination Risk
“Any higher throughput will, in turn, lower unit price. Automation within isolators allows the background to be held at Grade C, opposed to Grade B, which can reduce overhead contribution.”
In addi…
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Biopharma Advances Demand Specialized Expertise
Lorimer (Patheon Biologics): The main productivity improvement has been increasing the throughput of products in Patheon’s multiproduct biopharmaceutical GMP facilities. Single-use disposable bioreact…
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Continuous Manufacturing: A Changing Processing Paradigm
Employing straight-through processing in mAb purification could significantly improve throughput with a much smaller manufacturing footprint, presenters of the aforementioned webinar conclude. Case st…
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Introducing Supor Prime Filters: A Filtration Solution for High-Concentration Therapies
With twice the throughput, when compared to competitor filters, a smaller filter can be used which means less hold-up and more yield. For example, instead of using a 10 inch filter, a 5 inch filter ca…
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Top Tips for Successful Development of Antibody Chromatography Processes
…streamline downstream processing?
Jakob Liderfelt: I would really recommend utilizing high throughput tools, or different tools to increase the learnings during process development. High th…
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Report from the 6th International HTPD Conference
Alison Tang from AstraZeneca instead highlighted the issue with pH measurement: measuring pH accurately in a high throughput fashion using a small amount of sample has always been a challenge. Indeed,…
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Maximum Output Starts with Optimized Upstream Processing
The use of perfusion processes has enabled even larger throughputs within the same bioreactor volume.
Furthermore, Chilima observes that by using scalable technologies that have representative sca…
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Setting Up Bioprocessing Systems for Digital Transformation
High-fidelity models also identify the constraints that cause bottlenecks in throughput. “Any and all of these approaches are in use today. Predicting equipment failures, intensifying bioreactor titer…