Search results for "htpd"
Article
Development of Purification for Challenging Fc-Fusion Proteins
Using a combination of high-throughput process development (HTPD) in a 96-well batch binding format and small-scale column optimization experiments in a flow-through mode, the authors have developed a…
Article
High-Throughput Process Development Handbook
High-throughput process development (HTPD) shortens development time at the same time as it increases the amount of information available during early process development. Evaluating chromatographic c…
Poster
Accurate comparability assessment of a biosimilar interferon in process development
This is exemplified in this study by the use of these systems in the high-throughput process development (HTPD) of a biosimilar molecule, interferon α-2a (IFNα-2a).
Article
Q&As with Industry Leaders
…rtner at BioPlan Associates
3rd HTPD Conference
Phil Lester, Co-Organizer of the HTPD Conference
…
Article
Developing a HIC polishing step for removal of mAb aggregates
It includes:
- The use of HTPD plates to select the optimal resin as well as running conditions
- The use of a design of experiments (DoE) to optimize the running conditions
- A Monte Carlo simul…
Article
How to Use Multiwell Plates With Manual Operation
During process development, aspects like robustness, scalability, and GMP production come into play. FDA initiatives such as quality by design (QbD) put demands on better process understan…
Article
How Well Do You Know Process Development?
HTPD. DoE. Process understanding. Check your mastery of these and other essential terms by taking this quick quiz.
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Article
Tools and methodologies for smarter downstream process development
Scibetta
Smart process development is a collection of approaches to improve process outcomes and speed up process development.
In this video, John Scibetta, Advanced Chromatogra…
Article
Process Development: 2020 Reflections and 2021 Possibilities
One efficient method is high-throughput process development (HTPD), which streamlines various bioprocess workflows to enable enhanced efficiency with parallelization and automation of experiments.
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Article
Selecting Chromatography Formats for Your Process Development Workflow
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Development of robust purification processes requires significant time and resources. The quality-by-design initiative by the FDA puts additional demands on process deve…