Search results for " high-throughput"

Article 2019 HTPD Conference Abstract Submissions Are Coming Up: What Happened Last Time?
The HTPD conference series is the key international forum for the presentation and discussion of topics relevant to high-throughput process development and other approaches to smart PD for biopharmace…

Article Lessons Learned Accelerate Vaccine Development
“Quality by design, high-throughput screening, high-throughput sequencing, small-scale models to simulate large-scale production, artificial intelligence (both simulation and predictive models), and m…

Article Combining Microbioreactors and Advanced Statistical Techniques to Optimize a Platform Process for a New Host-Cell Line
First, the availability of high-throughput miniature bioreactors has made it possible to evaluate many more conditions. This has enabled design of experiment (DoE) approaches, such as response surface…

Article Fermentation for the Future
Given that there is a strong dependence between protein structure and performance of protein-based drugs, extensive refolding know-how and high-throughput screening capabilities are key to achieving t…

Article Predicting Progress in Protein Aggregation
As a result, significant efforts have been invested in understanding the mechanisms behind aggregation and the establishment of predictive models and more advanced analytical techniques, particularly …

Article Digitalization: The Route to Biopharma 4.0
Fully Automatized High-Throughput Enzyme Library Screening Using a Robotic Platform. Biotechnol Bioeng. 2016, 113 (7), 1421–1432. DOI: 10.1002/bit.25925. 4. Bielser, J. M.; Domaradzki, J.; Souqu…

Article Program finalized for the 6th HTPD and smart PD conference
As previously announced, the 6th International Conference devoted to High-Throughput Process Development (HTPD) and smart PD, will be held October 30-November 2, 2023 in Valetta, Malta. The HTPD confe…

Article HTPD 2023 conference is coming up. What will be discussed and what happened last time?
…tories here:  A new dawn for high throughput process development Applications of modern high-throughput process development Smart process development and a look into the future

Article Cell-free Expression Systems Pose Cell Culture Alternative
“For preclinical, we’ve already seen quite a lot of antibody production and high-throughput expression screening done in lab scale. But for clinical, the scale-up production is still under development…

Article Virus-like Particles as Therapeutic Moieties of the Future
SPR offers a high-throughput, rapid, label-free method to detect association of VLPs with their targets in real time (26). An IVRP assay reports the qualitative and quantitative epitope compos…

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