Search results for " high-throughput"
Article
Optimization of an antibody polishing step
Optimal operating conditions for single units are found by altering just a few process parameters with Design-of-Experiment (DoE) procedures or high-throughput screenings. But what if DoE fails to fin…
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Maximum Output Starts with Optimized Upstream Processing
“Efforts have targeted the development of new expression technologies, parallel tracking of activities that are not on the critical path, and implementing high-throughput, small-scale technologies,” c…
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Innovative Chromatography Resins Can Improve Purity and Quality
“Such improvements, combined with new tools, such as in-silico modeling of downstream processes and high-throughput screening of optimal process conditions at small scale, will enable a faster route t…
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Remote Monitoring and Big Data Advance Upstream Automation
In process development labs, for instance, he notes that the use of high-throughput culture systems such as the ambr15 and 250 from Sartorius have driven the need for automating sample handling and an…
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Process Development: 2020 Reflections and 2021 Possibilities
One efficient method is high-throughput process development (HTPD), which streamlines various bioprocess workflows to enable enhanced efficiency with parallelization and automation of experiments.
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Reimagining Affordable Biosimilars
…echniques allow simultaneous measurement of multiple product and process impurities in an automated, high-throughput mode. MS also offers an excellent orthogonal approach to traditional immunochemica…
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Highlights from the 5th International HTPD Conference, Part 3: Smart Process Development and a Look into the Future
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The high-throughput process development (HTPD) conference series is the key international forum for the presentation and discussion of topics relevant t…
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Maximizing the Effectiveness of Upstream Bioprocessing Through the Combination of Lab Informatics and Instrumentation
By establishing effective management of data and knowledge, it will be possible to employ advances, such as artificial intelligence and synthetic biology, to their full potential in upstream bioproc…
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Best Practices for Selecting a Top-Quality Cell Line
“In some platforms with lower transfection efficiencies, identifying high-expressing cell clones depends upon screening tens of thousands of clones, which is achievable using flow cytometry and high-t…
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Free On-Demand Webinar: Smart Process Development of Chromatography Steps
Use of high-throughput methodologies
This toolset can help you overcome some of the challenges with time limitations, a diversified pipeline, and more regulatory demands for more comprehensive d…