Search results for " in silico" in Articles / App Notes
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See a chromatography modeling software in action
Mechanistic models use computer simulations to decrease the number of experiments you need during process development.
The simulations are based on known physiochemical phenomena involved in ch…
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Accelerating VLP purification process development
Further, they allow for efficient process optimization in silico.
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Accelerate Downstream Process Development with Mechanistic Modeling
Learn how mechanistic models allow predictive modeling of your downstream process based on natural scientific principles.
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Mechanistic Modeling Resource Hub
Whether you’re planning experiments, looking for tools, or just curious about mechanistic modeling of chromatography, use this resource hub to stay informed and on track.
Learn more on mec…
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Setting Up Bioprocessing Systems for Digital Transformation
… may be simulated, with the time consuming, expensive, and labor-intensive experimentation performed in silico,” he states. Thus, deviations can be better investigated, and processes may be developed…
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Cell-Culture Advances Test Bioreactor Performance Models
…ir bioreactor networks empirically and heuristically, without the need for complex physical modeling in silico,” he asserts.
The key to successful modeling for the prediction of bioreactor perf…
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Modeling and Miniaturization: Key Topics at Successful HTPD Conference
Though the scale of the final process presented was significantly different, with a 300,000-L fermenter (!) producing the enzymes, similarities could be seen in both approach and challenges, with in s…
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Combining Microbioreactors and Advanced Statistical Techniques to Optimize a Platform Process for a New Host-Cell Line
The derived models were used to perform simultaneous in silico optimization of multiple process outputs. Optimization focused on increasing viability at harvest, reducing lactate accumulation at harve…
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Q&As with Industry Leaders
Discovering the unknown: How does in silico process development change PD scientists’ work?
Jeanne Linke Northrop, BioPharm International
Nora Ketterer, Manager, Modeling Services…
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Quality by design for biotechnology products—part 1
Nevertheless, the risk of immune response to a fully human antibody and other self proteins necessitates screening therapeutic protein candidates for immunogenicity using in silico methods, and in vit…