Search results for " bioprocessing"
Article
The Need for Advanced Process Modeling for New Therapeutic Biologics
As bioprocessing workflows increasingly shift toward automation, the approach to modeling also needs to evolve to incorporate next-generation tools and software. For example, how would process modelin…
Article
Single-Use for Downstream Chromatography: Benefit or Hindrance?
Reduction in bioprocessing time is one advantage that single-use systems offer. As Young points out, reusable systems can typically require more than 12 hours from set-up to tear-down, while single-us…
Article
The New World of Biopharmaceutical Manufacturing
Linz (Sartorius): In the past couple of years, we have seen just about every bioprocessing technology become available in a fully single-use format. Companies are implementing end-to-end single-use pl…
Article
Combining Microbioreactors and Advanced Statistical Techniques to Optimize a Platform Process for a New Host-Cell Line
Use of a subspace model is a viable method to characterize process space variables and optimize process performance.
By Colin Jaques, Daniela Lega
Over the past decade, two improved capabili…
Article
Top Process Development Trends for 2021 and a Look into 2022
The COVID-19 pandemic continues to shape bioprocess development trends, and many lessons have been learned from industry’s response to and preparedness for dealing with a public health crisis. Howev…
Article
Tools and Processes for Mature and Emerging Therapies
In April 2019, at the INTERPHEX trade show in New York City, vendors of bioprocessing equipment and materials announced improvements to existing platforms, added options for upstream and downstream sy…
Article
The Outlook for CMO Outsourcing in 2019
BioPlan Associates’ survey of bioprocessing professionals [3]overall confirms that outsourcing to CMOs is being viewed increasingly as a desirable option (1). Routine services and products with smalle…
Article
Digitalization: The Route to Biopharma 4.0
AI-ML Applications In Bioprocessing: ML as an Enabler of Real Time Quality Prediction in Continuous Manufacturing of Mabs. Computers & Chemical Engineering 2022, 164,107896. DOI: 10.1016/j.compchemeng…
Article
Industry Adoption of Single-Use Systems Remains Low
For these companies, the only viable option for manufacture of an in-house product candidate would likely be the use of single-use bioprocessing equipment, aside from outsourcing.
…
Article
A Q&A With Günter Jagschies: Recovery of Biological Products Conference Series
Could you share your viewpoint on the importance of this meeting?
The Recovery of Biological Products is probably the meeting most relevant to scientists, engineers, and managers in the bioprocess…