Search results for "Protein A" in Articles / App Notes
Article
Detailed agenda for Chromatography + filtration virtual summit
Explore the latest advancements in process development and scale-up
Check out the full agenda below!
Join Cytiva Chromatography and filtration summit online to learn from presentatio…
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The Importance of Process Intensification and PAT for Achieving Real-Time Release
More complex analyses, such as those required for protein and impurity identification and characterization, are conducted completely off-line. A sample is collected from the bioreactor and taken to a …
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Biosimilar Quality Requirements
This article reviews FDA’s recent efforts to streamline the biosimilar approval process and address quality concerns with the publication of new guidelines that suggest resources to aid in the biosi…
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Methods Accelerate Biosimilar Analysis
Methods Accelerate Biosimilar Analysis
Effective application of mass-spectrometry tools can optimize biosimilar analysis, reducing development time and cost.
By Mario DiPaola, …
Article
Addressing the Complex Nature of Downstream Processing with QbD
“For instance, protein A or affinity resins in general, as well as flow through steps, display these properties since these steps in most cases build on a fundamental understanding of the physiochemic…
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Ion Exchange Chromatography: Introducing New Capto™ HiRes Columns
• Designed for the preparation of highly pure proteins and for protein analysis, such as analysis of mAb charge variants.
• Replacing the well-established Mono Q™ and Mono S™ columns—with transiti…
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Combining Purification Techniques in a Multistep Approach
Looking for a purification protocol to reach yield and target purity of your protein? Setting up a multistep purification might be the way forward for your lab.
With the right combination of dif…
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Witnessing Major Growth in Next-Generation Antibodies
Including next-gen antibodies in pharma pipelines is considered essential for future success.
By Cynthia A. Challener
Next-generation antibodies are designed to be more specific and are ofte…
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Perfusion in the 21st Century
Quality, flexibility, and cost savings are driving use of perfusion technology in biosimilars manufacturing.
By Bruce Lehr, Delia Lyons
Cell-culture technology for biopharmaceutical manufact…
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Affinity chromatography Handbook - Vol. 3: Specific Groups of Biomolecules
Affinity chromatography (AC) separates proteins on the basis of a reversible interaction between a protein (or group of proteins) and a specific ligand coupled to a chromatography matrix. The techni…